Results 51 to 60 of about 27,550,913 (122)

Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing

Viruses, 2022
Determining the structural organisation of viral replication complexes and unravelling the impact of infection on cellular homeostasis represent important challenges in virology. This may prove particularly useful when confronted with viruses that pose a
Nicolas Tarbouriech, Florian Chenavier, Junna Kawasaki, Kamel Bachiri, Jean-Marie Bourhis, Pierre Legrand, Lily L. Freslon, Estelle M. N. Laurent, Elsa Suberbielle, Rob W. H. Ruigrok, Keizo Tomonaga, Daniel Gonzalez-Dunia, Masayuki Horie, Etienne Coyaud, Thibaut Crépin   +14 more
doaj   +1 more source

Investigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report

BMC Infectious Diseases, 2021
Background The true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far have been recorded in Bavaria, southern Germany.
Dennis Tappe, Kirsten Pörtner, Christina Frank, Hendrik Wilking, Arnt Ebinger, Christiane Herden, Christoph Schulze, Birgit Muntau, Petra Eggert, Petra Allartz, Gerlind Schuldt, Jonas Schmidt-Chanasit, Martin Beer, Dennis Rubbenstroth   +13 more
doaj   +1 more source

Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity

iScience, 2022
Summary: Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin.
Florent Henri Marty, Luca Bettamin, Anne Thouard, Karine Bourgade, Sophie Allart, Guilhem Larrieu, Cécile Evelyne Malnou, Daniel Gonzalez-Dunia, Elsa Suberbielle   +8 more
doaj   +1 more source

Active Case Finding of Current Bornavirus Infections in Human Encephalitis Cases of Unknown Etiology, Germany, 2018–2020

Emerging Infectious Diseases, 2021
Human bornavirus encephalitis is a severe and often fatal infection caused by variegated squirrel bornavirus 1 (VSBV-1) and Borna disease virus 1 (BoDV-1).
Philip Eisermann, Dennis Rubbenstroth, Daniel Cadar, Corinna Thomé-Bolduan, Petra Eggert, Alexander Schlaphof, Frank Leypoldt, Martin Stangel, Thorsten Fortwängler, Florian Hoffmann, Andreas Osterman, Sabine Zange, Hans-Helmut Niller, Klemens Angstwurm, Kirsten Pörtner, Christina Frank, Hendrik Wilking, Martin Beer, Jonas Schmidt-Chanasit, Dennis Tappe   +19 more
doaj   +1 more source

Molecular epidemiology of human Borna disease virus 1 infection revisited

Emerging Microbes and Infections, 2022
Borna disease virus 1 (BoDV-1) strains attracted public interest by recently reported rare fatal encephalitis cases in Germany. Previously, human BoDV-1 infection was suggested to contribute to psychiatric diseases.
Liv Bode, Yujie Guo, Peng Xie
doaj   +1 more source

Lethal Borna disease virus 1 (BoDV-1) infections of humans and animals – in-depth molecular epidemiology and phylogeography

, 2023
Abstract Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a progressive and mostly fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed shrew (Crocidura leucodon). The known BoDV-1 endemic area is remarkably restricted to
Dennis Rubbenstroth, Arnt Ebinger, Pauline Santos, Florian Pfaff, Ralf Dürrwald, Jolanta Kolodziejek, Kore Schlottau, Viktoria Ruf, Friederike Liesche-Starnecker, Armin Ensser, Klaus Korn, Reiner Ulrich, Jenny Fürstenau, Kaspar Matiasek, Florian Hansmann, Torsten Seuberlich, Daniel Nobach, Matthias Müller, Antonie Neubauer-Juric, Marcel Suchowski, Markus Bauswein, Hans-Helmut Niller, Barbara Schmidt, Dennis Tappe, Daniel Cadar, Timo Homeier-Bachmann, Viola Haring, Kirsten Pörtner, Christina Frank, Lars Mundhenk, Bernd Hoffmann, Jochen Herms, Wolfgang Baumgärtner, Norbert Nowotny, Jürgen Schlegel, Rainer G. Ulrich, Martin Beer   +36 more
openaire   +1 more source

Genome-wide profiling of long noncoding RNA expression patterns and CeRNA analysis in mouse cortical neurons infected with different strains of borna disease virus

Genes and Diseases, 2019
Borna disease virus 1 (BoDV-1) is neurotropic prototype of Bornaviruses causing neurological diseases and maintaining persistent infection in brain cells of mammalian species.
Lin Sun, Yujie Guo, Peng He, Xiaoyan Xu, Xiong Zhang, Haiyang Wang, Tian Tang, Wei Zhou, Ping Xu, Peng Xie   +9 more
doaj   +1 more source

Risk factors for Borna disease virus 1 encephalitis in Germany – a case–control study

Emerging Microbes and Infections, 2023
In 2018, Borna Disease Virus 1 (BoDV-1) was confirmed as a human zoonotic pathogen causing rare but fatal encephalitis in Germany. While diagnostic procedures and the clinical picture have been described, epidemiology remains mysterious.
Kirsten Pörtner, Hendrik Wilking, Christina Frank, Merle M. Böhmer, Klaus Stark, Dennis Tappe   +5 more
doaj   +1 more source

Shedding of Infectious Borna Disease Virus-1 in Living Bicolored White-Toothed Shrews. [PDF]

PLoS ONE, 2015
Many RNA viruses arise from animal reservoirs, namely bats, rodents and insectivores but mechanisms of virus maintenance and transmission still need to be addressed.
Daniel Nobach, Manon Bourg, Sibylle Herzog, Hildburg Lange-Herbst, Jorge A Encarnação, Markus Eickmann, Christiane Herden   +6 more
doaj   +1 more source

Vaccination against Borna Disease: Overview, Vaccine Virus Characterization and Investigation of Live and Inactivated Vaccines

Viruses, 2022
(1) Background: Vaccination of horses and sheep against Borna disease (BD) was common in endemic areas of Germany in the 20th century but was abandoned in the early 1990s.
Ralf Dürrwald, Jolanta Kolodziejek, Djin-Ye Oh, Sibylle Herzog, Heinrich Liebermann, Nikolaus Osterrieder, Norbert Nowotny   +6 more
doaj   +1 more source