Results 41 to 50 of about 3,069 (98)

Bornavirus Encephalitis Shows a Characteristic Magnetic Resonance Phenotype in Humans

open access: yesAnnals of Neurology, Volume 88, Issue 4, Page 723-735, October 2020., 2020
Objective The number of diagnosed fatal encephalitis cases in humans caused by the classical Borna disease virus (BoDV‐1) has been increasing, ever since it was proved that BoDV‐1 can cause human infections. However, awareness of this entity is low, and a specific imaging pattern has not yet been identified. We therefore provide the first comprehensive
Tom Finck   +12 more
wiley   +1 more source

Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing

open access: yesViruses, 2022
Determining the structural organisation of viral replication complexes and unravelling the impact of infection on cellular homeostasis represent important challenges in virology. This may prove particularly useful when confronted with viruses that pose a
Nicolas Tarbouriech   +14 more
doaj   +1 more source

Investigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report

open access: yesBMC Infectious Diseases, 2021
Background The true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far have been recorded in Bavaria, southern Germany.
Dennis Tappe   +13 more
doaj   +1 more source

Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity

open access: yesiScience, 2022
Summary: Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin.
Florent Henri Marty   +8 more
doaj   +1 more source

Active Case Finding of Current Bornavirus Infections in Human Encephalitis Cases of Unknown Etiology, Germany, 2018–2020

open access: yesEmerging Infectious Diseases, 2021
Human bornavirus encephalitis is a severe and often fatal infection caused by variegated squirrel bornavirus 1 (VSBV-1) and Borna disease virus 1 (BoDV-1).
Philip Eisermann   +19 more
doaj   +1 more source

Genome-wide profiling of long noncoding RNA expression patterns and CeRNA analysis in mouse cortical neurons infected with different strains of borna disease virus

open access: yesGenes and Diseases, 2019
Borna disease virus 1 (BoDV-1) is neurotropic prototype of Bornaviruses causing neurological diseases and maintaining persistent infection in brain cells of mammalian species.
Lin Sun   +9 more
doaj   +1 more source

Molecular epidemiology of human Borna disease virus 1 infection revisited

open access: yesEmerging Microbes and Infections, 2022
Borna disease virus 1 (BoDV-1) strains attracted public interest by recently reported rare fatal encephalitis cases in Germany. Previously, human BoDV-1 infection was suggested to contribute to psychiatric diseases.
Liv Bode, Yujie Guo, Peng Xie
doaj   +1 more source

Risk factors for Borna disease virus 1 encephalitis in Germany – a case–control study

open access: yesEmerging Microbes and Infections, 2023
In 2018, Borna Disease Virus 1 (BoDV-1) was confirmed as a human zoonotic pathogen causing rare but fatal encephalitis in Germany. While diagnostic procedures and the clinical picture have been described, epidemiology remains mysterious.
Kirsten Pörtner   +5 more
doaj   +1 more source

Shedding of Infectious Borna Disease Virus-1 in Living Bicolored White-Toothed Shrews. [PDF]

open access: yesPLoS ONE, 2015
Many RNA viruses arise from animal reservoirs, namely bats, rodents and insectivores but mechanisms of virus maintenance and transmission still need to be addressed.
Daniel Nobach   +6 more
doaj   +1 more source

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