Results 111 to 120 of about 3,032,119 (340)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Evaluation of influence of stretching therapy and ergonomic factors on postural control in patients with chronic non-specific low back pain

Annals of Agricultural and Environmental Medicine, 2015
Introduction The vertical orientation of the body in the upright standing position is maintained by keeping the body’s centre of gravity (COG) upright, above the base of support, by a dynamic interplay of visual, vestibular, and somatosensory control ...
Piotr Gawda, Magdalena Dmoszyńska-Graniczka, Halina Pawlak, Marek Cybulski, Michał Kiełbus, Piotr Majcher, Agnieszka Buczaj, Marcin Buczaj   +7 more
doaj   +1 more source

Application of the dual-kinetic-balance sets in the relativistic many-body problem of atomic structure

, 2007
The dual-kinetic-balance (DKB) finite basis set method for solving the Dirac equation for hydrogen-like ions [V. M. Shabaev et al., Phys. Rev. Lett. 93, 130405 (2004)] is extended to problems with a non-local spherically-symmetric Dirac-Hartree-Fock ...
Andrei Derevianko, Bachau, Blundell, Davidson, de Boor, Derevianko, Froese-Fischer, Goldman, Igarashi, Johnson, Johnson, Johnson, Kyle Beloy, Quiney, Shabaev   +14 more
core   +1 more source

Balancing energy expenditure and body weight [PDF]

The American Journal of Clinical Nutrition, 1998
It has been nearly 50 y since Mayer and coworkers hypothesized that the mechanisms controlling energy balance are accurate in persons with high levels of physical activity, but that in sedentary persons there is a threshold of physical activity below which these mechanisms become imprecise and that this leads to obesity.
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Features of body balance in 12-year-old schoolchildren with visual deprivation compared to their relatively healthy peers

Фізична реабілітація та рекреаційно-оздоровчі технології
Purpose. The purpose of the presented scientific research was to carry out a comparative analysis of the state of functional balance of the body of 12-year-old schoolchildren with visual deprivation in accordance with their relatively healthy peers ...
Bozhena Bukhovets, Vitalii Kashuba, Boris Dolinskiy, Olena Pogorelova, Volodymyr Boboshko   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Pengaruh Pemberian Static Balance Exercise Terhadap Peningkatan Keseimbangan Tubuh Pada Lanjut Usia Di Posyandu Menur Vi Dan Viii Desa Makamhaji Sukoharjo [PDF]

, 2016
Background: Setbacks and neuromuscular morphological changes that occur in the elderly will lead to functional changes. Functional changes that occur include decreased strength and muscle contractions, decreased muscle lasticity and flexibility, as well
, Dwi Kurniawati, SST.FT, M.Kes, Monnika, Lina   +1 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source