Results 101 to 110 of about 10,003,172 (407)

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Body fatness or anthropometry for assessment of unhealthy weight status? Comparison between methods in South African children and adolescents [PDF]

, 2013
A variety of methods are available for defining undernutrition (thinness/underweight/under-fat) and overnutrition (overweight/obesity/over-fat). The extent to which these definitions agree is unclear.
Armstrong, Baya Botti, Cole, Deurenberg, Eva Craig, John Reilly, Ruth Bland   +6 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Denz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

International society of sports nutrition position stand: diets and body composition

Journal of the International Society of Sports Nutrition, 2017
Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on a critical analysis of the literature regarding the effects of diet types (macronutrient composition; eating styles) and their influence on ...
Alan A Aragon, B. Schoenfeld, Robert Wildman, Susan M Kleiner, Trisha A. VanDusseldorp, L. Taylor, C. Earnest, P. Arciero, Colin Wilborn, D. Kalman, Jeffrey R. Stout, D. Willoughby, B. Campbell, S. Arent, Laurent G. Bannock, A. Smith‐Ryan, Jose Antonio   +16 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effects of Title IX and Sports Participation on Girls' Physical Ability and Weight [PDF]

, 2007
Summarizes findings from "Effects of Title IX and Sports Participation on Girls' Physical Ability and Weight," a study of how legislation to increase girls' participation in sports affected physical activity levels, body mass index, and body ...
Deanna Lewis, Robert Kaestner, Xin Xu
core  

Body composition and body fat distribution are related to cardiac autonomic control in non-alcoholic fatty liver disease patients [PDF]

, 2013
BACKGROUND/OBJECTIVES: Heart rate recovery (HRR), a cardiac autonomic control marker, was shown to be related to body composition (BC), yet this was not tested in non-alcoholic fatty liver disease (NAFLD) patients.
B Fernhall, C Panzer, CR Cole, DD Christou, DM Hadley, DP Vivekananthan, E Bertin, E Savgan-Gurol, EG Kamel, EO Nishime, ET Howley, F Kreier, G Nilsson, G Targher, GA Bray, H Cortez-Pinto, H Cortez-Pinto, H Nomura, H Santa-Clara, IJ Ketel, J Cohen, J Myers, J Silva-Nunes, JD Browning, JF Horowitz, JM Clark, K Imai, K Shetler, KM Chacko, L B Sardinha, LA Diaz, LR Davrath, M Cote, M da Lapa Rosado, M Gnacinska, M Lafontan, MA Kizilbash, MB Snijder, MJ Lipinski, MK Kim, MR Carnethon, MR Carnethon, MR Esco, MS Chen, N M Pimenta, NM Pimenta, P Angulo, P J Sousa, R Arena, R Calé, RA Bruce, RS Rector, S Bellentani, TA Hargens, TG Lohman, TJ Bartness, X Melo, YJ Cheng, YW Park   +58 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Higher rating of perceived exertion and lower perceived recovery following a graded exercise test during menses compared to non-bleeding days in untrained females

Frontiers in Physiology
The underrepresentation of the female population in exercise sciences could be attributed, at least in part, to difficulty in appropriately accounting for the effects of the menstrual cycle (MC).
Morgan Delp, Grant A. Chesbro, Brian A. Pribble, Ryan M. Miller, Hugo M. Pereira, Christopher D. Black, Rebecca D. Larson   +6 more
doaj   +1 more source