Results 71 to 80 of about 10,003,172 (407)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Body Composition Changes in Weight Loss: Strategies and Supplementation for Maintaining Lean Body Mass, a Brief Review

open access: yesNutrients, 2018
With over two-thirds (71.6%) of the US adult population either overweight or obese, many strategies have been suggested for weight loss. While many are successful, the weight loss is often accompanied by a loss in lean body mass.
D. Willoughby, S. Hewlings, D. Kalman
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

The evolution of body composition in oncology—epidemiology, clinical trials, and the future of patient care: facts and numbers

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2018
There is growing interest from the oncology community to understand how body composition measures can be used to improve the delivery of clinical care for the 18.1 million individuals diagnosed with cancer annually.
Justin C. Brown   +2 more
semanticscholar   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

The Change of Body Composition of Indigenous Rams on Different Body Weight and Feeding Level [PDF]

open access: yes, 2009
The aim of this research was to investigate the influence of body weight and feeding level on the changeof body composition of indigenous ram. This research was expected to establish the efficient feeding levelto produce high growth rate and meat quality
Mahesti, G. (G)   +4 more
core  

Motives for exercising and associations with body composition in Icelandic adolescents [PDF]

open access: yes, 2019
The aim of this study is to identify and analyze the motives that lead Icelandic teenagers to engage in physical exercise and the possible associations with variables of their body composition.
Galán López, Pablo, Ries, Francis
core   +2 more sources

Exercise, energy balance and body composition

open access: yesEuropean Journal of Clinical Nutrition, 2018
Activity-induced energy expenditure, as determined by the activity pattern including exercise, is the most variable component of daily energy expenditure.
K. Westerterp
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

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