Results 91 to 100 of about 1,397,288 (296)

Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants [PDF]

open access: yes, 2017
Background: Obesity is a multifactorial condition influenced by both genetics and lifestyle. The aim of this study was to investigate whether the association between a validated genetic profile risk score for obesity (GPRS-obesity) and body mass index ...
Anderson, Jana   +13 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluation of the Prevalence and Risk Factors for Undernutrition in Hospitalized Dogs

open access: yesFrontiers in Veterinary Science, 2018
Hospitalized dogs are predisposed to undernutrition, which can potentially affect outcome. This study evaluated the prevalence of undernutrition in hospitalized dogs (measured as loss of body condition score, BCS and body weight, BW) and studied the risk
Jenifer Molina   +7 more
doaj   +1 more source

Body condition score, weight variation and reproductive performance of beef cows in rangelands from the Pantanal region [PDF]

open access: yes, 2009
Objetivou-se avaliar a influência do escore de condição corporal (ECC) sobre a eficiência reprodutiva de vacas de cria nos períodos pré e pós-parto e a probabilidade de parição, usando o escore de condição corporal e a variação ponderal no período ...
ABREU U.G.P   +25 more
core   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Associations among body condition score, body weight, and serum biochemistry in dairy cows

open access: yesJournal of Dairy Science
: Body condition score and BW yield insights into body tissue reserves and diet, and serum biochemical measures reflect the metabolic status of cows. Associations between body composition measures and biochemistry are unclear and investigation may reveal
David B. Sheedy   +8 more
doaj   +1 more source

Evaluation of the use of milk urea nitrogen (MUN) as an indicator of nutritional status of dairy cattle in smallholder farms in Kiambu district [PDF]

open access: yes, 2010
A survey was conducted to evaluate the use of Milk Urea Nitrogen as an indicator of nutrition status of lactating animals. Twenty-seven animals in a randomly selected sample of 21 farms in Kiambu District were monitored for nutritional status for 12 ...
Gachuiri, C.   +4 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Influence of Beginning Body Condition Scores on Net Returns From Feeding Cull Cows [PDF]

open access: yes
The impact of beginning body condition scores on returns from feeding cull cows was investigated in a two year experiment. In each of two culling years, physical performance data and financial data were measured at approximately monthly intervals for ...
Amadou, Zakou   +4 more
core   +1 more source

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