Results 111 to 120 of about 527,288 (298)

Michael Neary, Extension Animal Scientist Ann Yager, Animal Sciences Student

open access: yes, 2007
Knowing how to body condition score is useful for individual animals, as well as for the herd or flock in general. Herd owners, or professionals in the animal care field, can make the proper adjustments to their feeding or health programs to reach the ...
As- Body Condition
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Genome-wide associations for milk production and somatic cell score in Holstein-Friesian cattle in Ireland

open access: yes, 2012
peer-reviewedBackground: Contemporary dairy breeding goals have broadened to include, along with milk production traits, a number of non-production-related traits in an effort to improve the overall functionality of the dairy cow.
David J Lynn   +20 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Excessive lipid contents in immature oocytes from repeat breeder dairy heifers

open access: yes, 2006
The repeat breeding problem in cattle is widespread among all the heavy dairy breeds in cattle and is being considered as a major problem throughout the world. The aetiology of the repeat breeding is of various origins.
Awasthi, Hitesh
core  

Correlations between acute phase proteins and the body condition score

open access: yes, 2017
The objective of this study was to evaluate the dynamics of the body condition score, acute phase proteins (serum amyloid A and haptoglobin) and their relationships in dairy cows of the Slovak Pied Cattle from 3 weeks before parturition to 9 weeks after ...
Katarína Veszelits Laktičová   +5 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Comparison of growth curves of three strains of female dairy cattle

open access: yes, 2005
peer-reviewedThe objective of the present study was to compare growth curves for live weight (LW) and body size of three strains of female dairy cattle reared under common environments in Ireland.
Dillon, Pat   +2 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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