Results 131 to 140 of about 7,463,330 (288)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The relationship between canine body condition score and hematologic profile [PDF]

open access: yesWarasan Witthayasat Lae Theknoloyi Mahawitthayalai Mahasarakham, 2019
This study aims to investigate the correlation between the body condition score (BCS) and hematological profiles of stray dogs in Maha Sarakham province.
Thanaporn Asawapattanakul
doaj  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Feeding Dairy Cows for Body Condition Score [PDF]

open access: yes, 2008
Changes in body weight are not a very good indicator of the nutritional status of dairy cows. For example, while the gut contents of a 1400 lb. dairy cow weigh approximately 200 lbs., the cow has a daily intake of nearly 100 lbs.
Garcia, Alvaro, Hippen, Arnold
core   +1 more source

Yearly changing of body condition score of karya type sheep [PDF]

open access: yes, 2008
Bu çalışma, Aydın yöresinde bulunan Karya Tipi koyunlarda vücut kondisyonunun yıllık değişimini ve vücut kondisyonu ile kuzu verimi arasındaki ilişkiyi tanımlamak amacıyla yapılmıştır.
Özdemir, Yeşim
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EFFECT OF PRE-CALVING BCS ON POSTPARTUM BCS AND BODY WEIGHT CHANGE OF SAHIWAL CATTLE [PDF]

open access: yesExploratory Animal and Medical Research, 2019
A total of 18 Sahiwal cattle of 1st to 4th parity were selected for the study and distributed into three different groups based on their pre calving body condition score (BCS) (before 15 days of expected date of calving) namely G1 (2.50 - 3.00), G2 (3 ...
V. Sharma   +5 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

G92-1070 Feeding Dairy Cattle for Proper Body Condition Score [PDF]

open access: yes, 1992
This NebGuide describes feeding and management practices that allow the producer to control body condition throughout lactation and the dry period. Body condition score is a critical measure of a dairy feeding system\u27s effectiveness. Adequate body fat
Keown, Jeffrey F., Grant, Rick
core  

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