Results 141 to 150 of about 7,463,330 (288)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Michael Neary, Extension Animal Scientist Ann Yager, Animal Sciences Student
, 2007 Knowing how to body condition score is useful for individual animals, as well as for the herd or flock in general. Herd owners, or professionals in the animal care field, can make the proper adjustments to their feeding or health programs to reach the ...
As- Body Condition
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Validating bottlenose dolphins (Tursiops truncatus) body condition score
, 2017 Concerns regarding the health of all animals under human care have increased significantly over the past several years. Body condition scores serve as accepted measures of the overall health of several species of animals in agricultural and laboratory ...
Patterson, Kelly
core +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The use of new practices for assessment of body condition score [PDF]
Revista Mvz Cordoba, 2015 Objective. Two body condition scoring systems were compared to those of interpretation of cow’s body condition at a local farm located in Aydin region, Turkey. Materials and methods.
Deniz Alic Ural
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Energy balance and its relationship to body weight and body condition in grazing horses
Czech Journal of Animal ScienceEquine obesity currently represents a significant welfare concern, with its development influenced by seasonal changes in the nutritional value of pasture, which substantially affect the animals' energy balance.
Eva Mlyneková +4 more
doaj +1 more source