Results 71 to 80 of about 851,018 (304)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Rights of Passage: Majority Rule in Congress [PDF]
The United States government is a government not of rigorously separated powers, but of overlapping and concurrent powers: a government of checked and balanced powers. What strikes the balance? A few spare words of the Constitution.
Rubenfeld, Jed
core +2 more sources
The Doctrine of Exhaustion of Union Remedies [PDF]
High-k/metal gate stacks have been introduced in CMOS technology during the last decade in order to sustain continued device scaling and ever-improving circuit performance.
Montemuro, Frank J., Jr.
core +3 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
О ЧЕМ РАССКАЖЕТ ПЕДАГОГУ КОНСТИТУЦИЯ ТЕЛА СТУДЕНТА [PDF]
У статті розглянуто існуючі класифікації типів конституції людини, встановлено мету та завдання експериментального дослідження, розкрито методику проведення експерименту.
Неведомська, Євгенія Олексіївна
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Empower users of financial information as the IASC Foundation's stakeholders [PDF]
Nicolas Véron comments on the proposal for governance reform (Â?constitution reviewâ??) published in May 2008 by the IASC Foundation, the private-sector body which oversees the setting of International Financial Reporting Standards (IFRS).
Nicolas Véron
core +1 more source
Framework for Understanding the Legal Structure of Texas Public Schools [PDF]
Texas public school stakeholders consist primarily of students, parents, faculty and staff, administrators, school board members, business leaders, community members, and taxpayers.
Bigham, Gary
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
BackgroundBased on the Chinese Medicine constitution, this study developed a questionnaire specifically tailored for preschool children.MethodsFirst, a TCM constitution scale for children aged 3–6 years was developed using face-to-face interviews, Delphi
Wenle Li +8 more
doaj +1 more source

