Results 71 to 80 of about 851,018 (304)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Rights of Passage: Majority Rule in Congress [PDF]

open access: yes, 1996
The United States government is a government not of rigorously separated powers, but of overlapping and concurrent powers: a government of checked and balanced powers. What strikes the balance? A few spare words of the Constitution.
Rubenfeld, Jed
core   +2 more sources

The Doctrine of Exhaustion of Union Remedies [PDF]

open access: yes, 1952
High-k/metal gate stacks have been introduced in CMOS technology during the last decade in order to sustain continued device scaling and ever-improving circuit performance.
Montemuro, Frank J., Jr.
core   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

О ЧЕМ РАССКАЖЕТ ПЕДАГОГУ КОНСТИТУЦИЯ ТЕЛА СТУДЕНТА [PDF]

open access: yes, 2014
У статті розглянуто існуючі класифікації типів конституції людини, встановлено мету та завдання експериментального дослідження, розкрито методику проведення експерименту.
Неведомська, Євгенія Олексіївна
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Empower users of financial information as the IASC Foundation's stakeholders [PDF]

open access: yes
Nicolas Véron comments on the proposal for governance reform (Â?constitution reviewâ??) published in May 2008 by the IASC Foundation, the private-sector body which oversees the setting of International Financial Reporting Standards (IFRS).
Nicolas Véron
core   +1 more source

Framework for Understanding the Legal Structure of Texas Public Schools [PDF]

open access: yes, 2018
Texas public school stakeholders consist primarily of students, parents, faculty and staff, administrators, school board members, business leaders, community members, and taxpayers.
Bigham, Gary
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A scale for assessing the health of children aged 3–6 years in China: development and validation of the TCM constitution scale (3–6 years)

open access: yesFrontiers in Public Health
BackgroundBased on the Chinese Medicine constitution, this study developed a questionnaire specifically tailored for preschool children.MethodsFirst, a TCM constitution scale for children aged 3–6 years was developed using face-to-face interviews, Delphi
Wenle Li   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy