Results 81 to 90 of about 1,527,089 (339)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. [PDF]
, 2019 Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted coding and splice site ...
Abecasis, Goncalo +99 more
core
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Dual-energy X-ray absorptiometry scans accurately predict differing body fat content in live sheep
Journal of Animal Science and Biotechnology, 2018 Background There is considerable interest in implementing mobile scanning technology for on-farm body composition analysis on live animals. These experiments evaluated the use of dual energy X-ray absorptiometry (DXA) as an accurate method of total body ...
David W Miller +4 more
doaj +1 more source
Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
FEBS Open Bio, EarlyView.Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski +13 more
wiley +1 more source
Body fat composition as a marker for risk assessment in hypertension
Journal of Marine Medical Society, 2017 Introduction: High blood pressure (BP) is one of the most common chronic medical problems prompting visits to primary health-care providers. The incidence of lifestyle diseases over the years has shown an upward trend in developing countries too, which ...
S Vijay Bhaskar +2 more
doaj +1 more source
Cross-sectional and prospective impact of reallocating sedentary time to physical activity on children's body composition. [PDF]
, 2016 BACKGROUND: The amount of time children spend in sedentary behaviours may have adverse health effects. OBJECTIVE: To examine the substitution effects of displacing a fixed duration of sedentary time with physical activity (PA) on children's body ...
Ekelund, Ulf +3 more
core +2 more sources
Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments
FEBS Open Bio, EarlyView.Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau +3 more
wiley +1 more source
Efficacy of exercise counselling as an aid for smoking cessation: a randomized controlled trial. [PDF]
, 2003 To examine whether exercise counselling increases smoking abstinence and reduces tobacco withdrawal and gains in weight and body ...
Adrian Taylor +51 more
core +1 more source
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source