Results 51 to 60 of about 7,158,834 (368)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Indian Journal of Pathology and Microbiology, 2019 Introduction: Automated body fluid (BF) analysis is gradually replacing the traditional methods of cell counting in all BFs. This study was done to analyze the high-fluorescence (HF)-BF parameter generated on Sysmex XN-1000 and study its correlation with
Loveena Rastogi +3 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Korean Journal of Clinical Laboratory Science, 2022 In clinical practice, the diagnosis of tuberculosis (TB) continues to be a challenge. The goal of this study was to evaluate the reliability and impact of adenosine deaminase (ADA) enzyme testing as a biochemical marker in the continued management of ...
Rafia Rasool +4 more
doaj +1 more source
On the trajectory of a light small rigid body in an incompressible viscous fluid [PDF]
arXiv, 2022 In this paper we study the dynamics of a small rigid body in a viscous incompressible fluid in dimension two and three. More precisely we investigate the trajectory of the rigid body in the limit when the its mass and its size tend to zero. We show that the velocity of the center of mass of the rigid body coincides with the background fluid velocity in
arxiv
Forensic body fluid identification: state of the art
, 2016 Body fluid identification is a key component in the forensic scientists' tool box and has been carried out both at the crime scene and in the laboratory for many years.
S. Harbison, R. Fleming
semanticscholar +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
On the weak uniqueness of "viscous incompressible fluid + rigid body" system with Navier slip-with-friction conditions in a 2D bounded domain [PDF]
, 2018 The existence of weak solutions to the "viscous incompressible fluid + rigid body" system with Navier slip-with-friction conditions in a 3D bounded domain has been recently proved by G\'{e}rard-Varet and Hillairet in \cite{exi:GeH}. In 2D for a fluid alone (without any rigid body) it is well-known since Leray that weak solutions are unique, continuous ...
arxiv +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Proteomes, 2019 Extracellular vesicles (EVs) are a highly attractive subject of biomedical research as possible carriers of nucleic acid and protein biomarkers. EVs released to body fluids enable indirect access to inner organs by so-called “liquid biopsies”.
Helena Kupcova Skalnikova +6 more
doaj +1 more source