Results 81 to 90 of about 7,158,834 (368)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

On the 2D `viscous incompressible fluid + rigid body' system with Navier conditions and unbounded energy [PDF]

open access: yesarXiv, 2018
In this paper we consider the motion of a rigid body in a viscous incompressible fluid when some Navier slip conditions are prescribed on the body's boundary. The whole `viscous incompressible fluid + rigid body' system is assumed to occupy the full plane $\R^{2}$.
arxiv  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

The role of body flexibility in stroke enhancements for finite-length undulatory swimmers in viscoelastic fluids [PDF]

open access: yes, 2016
The role of passive body dynamics on the kinematics of swimming micro-organisms in complex fluids is investigated. Asymptotic analysis of small amplitude motions of a finite-length undulatory swimmer in a Stokes-Oldroyd-B fluid is used to predict shape changes that result as body elasticity and fluid elasticity are varied. Results from the analysis are
arxiv   +1 more source

Global weak solutions to a 3D/3D fluid-structure interaction problem including possible contacts [PDF]

open access: yesarXiv, 2023
In this paper, we study an interaction problem between a $3D$ compressible viscous fluid and a $3D$ nonlinear viscoelastic solid fully immersed in the fluid, coupled together on the interface surface. The solid is allowed to have self-contact or contact with the rigid boundary of the fluid container. For this problem, a global weak solution with defect
arxiv  

Body Fluid Cytokine Levels in Mild Cognitive Impairment and Alzheimer’s Disease: a Comparative Overview

open access: yesMolecular Neurobiology, 2014
This article gives a comprehensive overview of cytokine and other inflammation associated protein levels in plasma, serum and cerebrospinal fluid (CSF) of patients with Alzheimer’s disease (AD) and mild cognitive impairment (MCI).
F. Brosseron   +3 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Next step of molecular pathology: next-generation sequencing in cytology [PDF]

open access: yesJournal of Pathology and Translational Medicine
The evolving landscape of precision oncology underscores the pivotal shift from morphological diagnosis to treatment decisions driven by molecular profiling.
Ricella Souza da Silva, Fernando Schmitt
doaj   +1 more source

Non-Exosomal and Exosomal Circulatory MicroRNAs: Which Are More Valid as Biomarkers?

open access: yesFrontiers in Pharmacology, 2020
MicroRNAs (miRNAs) are a group of small non-coding RNAs with approximately 19–25 nucleotides that are involved in regulating a range of developmental and physiological processes.
Nik Nur Syazana Binti Nik Mohamed Kamal   +1 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

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