Results 51 to 60 of about 241,305 (216)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Obstetric Brachial Plexus Palsy and Functional Implications: Which Joint in the Upper Extremity Is More Closely Associated?

Medicina
Background and Objectives: The objective of this study is to examine the correlation between the active range of motion (ROM) of the affected upper extremity and functional capacity in children with Obstetric Brachial Plexus Palsy (OBPP) who have ...
Gülsena Utku Umut, Zeynep Hoşbay, Müberra Tanrıverdi, Güleser Güney Yılmaz, Okyar Altaş, Alperen Korucu, Atakan Aydın   +6 more
doaj   +1 more source

An investigation of individual functionality football referees of high qualification

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2014
Purpose: to determine the level of individual functionality arbitrators of high qualification. Material : in the experiment participated 29 high qualification arbitrators aged 21-45 years.
T.G. Chopilko
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Sport for All at ESECS - a pilot project with people with Intellectual and Developmental Disabilities (IDD)

Motricidade
The relationship between the levels of autonomy and independence in people with Intellectual and Developmental Disabilities (IDD) and their levels of functional physical fitness is not clear in the literature.
Raul Antunes, Alexandra Curado, Diogo Monteiro, Nuno Amaro, Rui Matos, Filipe Rodrigues, Miguel Jacinto   +6 more
doaj   +1 more source

Exploring the human body space: A geographical information system based anatomical atlas

Journal of Spatial Information Science, 2016
Anatomical atlases allow mapping the anatomical structures of the human body. Early versions of these systems consisted of analogical representations with informative text and labeled images of the human body.
Antonio Barbeito, Marco Painho, Pedro Cabral, João Goyri O'Neill   +3 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source