Results 41 to 50 of about 833,173 (305)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Increased choroidal thickness in patient with high-altitude retinopathy
Indian Journal of Ophthalmology, 2014 We report a case of high-altitude retinopathy with increased choroidal thickness detected by spectral-domain optical coherence tomography (SD-OCT). A 36-year-old Japanese man developed an acute vision decrease in his left eye after he had trekked at an ...
Kyoko Hirukawa-Nakayama +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Ophthalmic masquerades of the atherosclerotic carotids
Indian Journal of Ophthalmology, 2014 Patients with carotid atherosclerosis can present with ophthalmic symptoms. These symptoms and signs can be due to retinal emboli, hypoperfusion of the retina and choroid, opening up of collateral channels, or chronic hypoperfusion of the globe (ocular ...
Anupriya Arthur +4 more
doaj +1 more source
Birthweight, Childhood Body Mass Index, Height and Growth, and Risk of Polycystic Ovary Syndrome
Obesity Facts, 2021 Introduction: Adult obesity is linked with polycystic ovary syndrome (PCOS), but the importance of body size at ages before PCOS is diagnosed is unknown. Objective: To investigate associations between a woman’s own birthweight, childhood body mass index (
Julie Aarestrup +6 more
doaj +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
BMC Musculoskeletal DisordersBackground Proper muscle tension is an essential element for correct body posture and motion. It should be high enough to counteract gravity and low enough to provide smooth, selective movement and isolated activity.
Mirosław Mrozkowiak +2 more
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BODY WEIGHT AT DIFFERENT AGES AND HEIGHTS [PDF]
Annals of Eugenics, 1951 The articles published by the Annals of Eugenics (1925–1954) have been made available online as an historical archive intended for scholarly use. The work of eugenicists was often pervaded by prejudice against racial, ethnic and disabled groups. The online publication of this material for scholarly research purposes is not an endorsement of those views
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem +17 more
wiley +1 more source
A survey of Height and Weight of Students Aged 11-17 Years in Hamadan
پزشکی بالینی ابن سینا, 1998 Normal growth is the best indicator of children’s health and well-being. Measuring height and weight is the simplest way of eveluation of growth. In this study the height and weight of 1481 students of Hamadan aging 11-17 was measured and analyzed.
Mohammadreza Derakhshan
doaj