Results 51 to 60 of about 2,067,102 (305)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A survey of Height and Weight of Students Aged 11-17 Years in Hamadan

open access: yesپزشکی بالینی ابن سینا, 1998
Normal growth is the best indicator of children’s health and well-being. Measuring height and weight is the simplest way of eveluation of growth. In this study the height and weight of 1481 students of Hamadan aging 11-17 was measured and analyzed.
Mohammadreza Derakhshan
doaj  

Human Center of Gravity Dynamics a New Parameter of Motor Development Functions [PDF]

open access: yes, 2001
A study of a new parameter of human growth and development was conducted. The percentage of the height of body gravity center to the stature in supine position was measured in males and females during the period of pre-puberty (l995), young and adult ...
Sofwanhadi, R. (Rio)
core  

Transverse Ising Chain under Periodic Instantaneous Quenches: Dynamical Many-Body Freezing and Emergence of Solitary Oscillation

open access: yes, 2012
We study the real-time dynamics of a quantum Ising chain driven periodically by instantaneous quenches of the transverse field (the transverse field varying as rectangular wave symmetric about zero).
Bhattacharyya, Sirshendu   +2 more
core   +1 more source

Estimation Bias: Body Mass and Body Height in Endurance Athletes

open access: yesPerceptual and Motor Skills, 2012
Body Mass Index is associated with endurance performance in athletes. Reported and measured values of body mass and body height in 1,618 endurance athletes (1,358 men, 260 women) showed that men and women both underestimated their body mass and overestimated their body height, leading to an underestimation of Body Mass Index.
Knechtle, Beat   +4 more
openaire   +4 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The effect of plyometric exercise on bone mineralisation and physical fitness in adolescents

open access: yesPhysiotherapy Quarterly
Introduction Plyometric exercise is the preferred type of exercise to promote bone health due to its role on providing high-impact loading of bone tissue.
Syahrul Syahrul   +3 more
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

The Accuracy of the Broselow™ Pediatric Emergency Tape for Weight Estimation in an Omani Paediatric Population

open access: yesSultan Qaboos University Medical Journal, 2017
Objectives: This study aimed to evaluate the accuracy of the Broselow™ Pediatric Emergency Tape (BT) for estimating weight in an Omani paediatric population at a tertiary care hospital.
Azher A. Al-Busaidi   +2 more
doaj   +1 more source

Serum osmolarity and haematocrit do not modify the association between the impedance index (Ht2/Z) and total body water in the very old: The Newcastle 85+ Study [PDF]

open access: yes, 2015
Bioelectrical impedance is a non-invasive technique for the assessment of body composition; however, information on its accuracy in the very old (80+ years) is limited.
Collerton, Joanna   +9 more
core   +1 more source

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