Results 101 to 110 of about 1,124,762 (311)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2011 The diagnosis and treatment of cancer can result both physical and psychiatric morbidity. Physical and psychological changes during the course of cancer may alter an individual's body image.
Sertöz O.O.
core
Approaches to Body Image Change
Florence Nightingale Journal of Nursing, 2019 In this article the three components of body image -body reality, body ideal and body presantation- and how they affect each other has been described and there importance for self,image has been emphasized.
Gülten ÖZALTIN
doaj
Eating and Weight DisordersObjective The Eating Disorder Examination-Questionnaire (EDE-Q) is a widely used 28-item instrument for screening eating disorders, of which 22 are attitudinal items used to compute subscale scores and to assess factorial structure, while six open-ended ...
Andreia Dutra Gonçalves +3 more
doaj +1 more source
Konsep Body Image Remaja Putri
Jurnal Konseling dan Pendidikan, 2015 Munculnya penilaian dikalangan remaja putri standar tubuh saat ini yang mementingkan penampilan fisik dengan bentuk tubuh yang proposional, telah membuat remaja putri saat ini menjadi kurang percaya diri, remaja putri selalu menilai dirinya melalui kaca ...
Amandha Unziila Denich, Ifdil Ifdil
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Editorial: Experimental Approaches to Body Image, Representation and Perception
Frontiers in Psychology, 2021 Kevin R. Brooks +7 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Body image quality of life in eating disorders
Patient Preference and Adherence, 2011 Ignacio Jáuregui Lobera1, Patricia Bolaños Ríos21Department of Nutrition and Bromatology, Pablo de Olavide University, Seville, Spain; 2Behavior Sciences Institute, Seville, SpainPurpose: The objective was to examine how ...
Ignacio Jáuregui Lobera +1 more
doaj