Results 71 to 80 of about 2,892,369 (330)
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Body Image in Long Distance Runners [PDF]
, 2018 In lieu of an abstract, below is the essay\u27s first paragraph. How would you describe the ideal runner’s body? Would you say it is tall or short? Skinny or fat? Muscular or lean? Is it the same as society’s ideal female’s body?
Hull, Meghan
core +1 more source
Body image importance and body dissatisfaction among Indigenous Australian adolescents
, 2004 Despite their elevated risk of health problems and a propensity to be more overweight or underweight relative to the other members of the Australian population, there has been no previous investigation of body image concerns among Indigenous Australians.
Ball, Kylie +3 more
core +1 more source
Body Image Avoidance, Body Dissatisfaction, and Eating Pathology
American Journal of Men's Health, 2016 With research highlighting the increasing prevalence and severity of body image and eating disturbances in males, particularly athletes and regular gymnasium users, the current study examined body image and eating disturbances in a sample of male gym ...
Peta Stapleton PhD +2 more
doaj +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Teaching Body Image to EFL Teenagers [PDF]
, 2010 An extract of an Upper-Intermediate EFL coursebook for teenage learners I designed in partial requirement for MA Applied Linguistics & English Language Teaching.\ud \ud The material is centred about the topic of 'Body Image' and includes a focus on ...
Clark, Miss `Victoria L
core
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Acceptance of psoriasis in the context of body image, body experience, and social support
Health Psychology Report, 2017 Background Acceptance of disease is an important determinant of quality of life in psoriasis patients. Social support and positive body image are considered important contributors to coping with the disease, but no studies have yet examined the role of
Olga Sakson-Obada +3 more
doaj +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source