Results 71 to 80 of about 1,402,107 (261)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Postura corporal: um problema que aflige os trabalhadores

Revista Brasileira de Saúde Ocupacional
Este artigo aborda primeiramente, aspectos e entendimento dos autores referentes às definições de postura corporal, os mecanismos responsáveis pela sua manutenção, qual é a postura considerada adequada ou inadequada, os distúrbios e medidas de prevenção.
Mariângela Gagliardi Caro Salve, Antonia Dalla Pria Bankoff   +1 more
doaj   +1 more source

Case-control study of anthropometric measures and testicular cancer risk

Frontiers in Endocrinology, 2012
The etiology of testicular germ cell tumors (TGCTs) is poorly understood. Recent epidemiological findings suggest that TGCT risk is determined very early in life, although the available data are still conflicting.
Fabrizio eGiannandrea, Donatella ePaoli, Francesco eLombardo, Andrea eLenzi, Loredana eGandini   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Revista Brasileira de Cineantropometria e Desempenho Humano, 2014
The aim of this study was to compare the values obtained through methods directed to height and body weight estimates in relation to measurements taken from hospitalized adult. Study participants were 142 adults of both genders.
Ana Paula Ferreira Melo, Raquel Kuerten de Salles, Francilene Gracieli Kunradi Vieira, Marilyn Gonçalves Ferreira   +3 more
doaj  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

PRECAUTIONARY MEASURES IN CRIMINAL PROCEEDINGS [PDF]

Challenges of the Knowledge Society
Precautionary measures are an area that is constantly being adapted, due to their importance both for the proper conduct of the criminal proceedings and because of their implications affecting the constitutionally recognized rights of the suspect, the ...
Monica Cristina COSTEA
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Quasi-Experiment of Self-Weight Combined with Dietary and Physical Activity to Reduce Postpartum Weight Retention

Iranian Journal of Nursing and Midwifery Research
Background: The failure to lose postpartum weight retention (PPWR) can impact obesity in later life, making programs aimed at reducing PPWR crucial.
Piyanut Xuto, Punpilai Sriarporn, Sayamon Cotchapanya, Tatsawan Sunanta, Tareewan Chaiboonruang   +4 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source