Results 31 to 40 of about 42,537 (263)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Bookchin’s libertarian municipalism

open access: yesCadernos de Campo, 2019
The purpose of this article is to present the Libertarian Municipalism Theory developed by Murray Bookchin. The text is divided into two sections. The first section presents the main precepts of Libertarian Municipalism.
Janet Biehl
doaj  

The Pope’s Two Bodies: A Note on Medieval Juridical Theology

open access: yesExceptions: European Journal of Critical Jurisprudence
The medieval Papal Revolution was the first successful attempt by a body of intellectuals to affirm what we would now call the political priority of principles.
Riccardo Baldissone
doaj   +1 more source

The Monk by M. G. Lewis: Revolution, Religion and the Female Body

open access: yesText Matters, 2016
This paper reads The Monk by M. G. Lewis in the context of the literary and visual responses to the French Revolution, suggesting that its digestion of the horrors across the Channel is exhibited especially in its depictions of women.
Agnieszka Łowczanin
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Unsteady test technique of jet control with multi-parameter coupling

open access: yesAdvances in Mechanical Engineering, 2022
In this paper, the jet control effect of air vehicle is studied, and a new multi parameter coupling unsteady test technique is established, which can ensure that the test model is consistent with the real air vehicle, and the jet is carried out under the
Fei Xue   +4 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Cultural Dimension of Revolution: New Images of Man

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2017
The turning points of the history are characterized by people’s active participation in one of the most natural for the man social activity – the creation of new self-images.
Maksim M. Zagorulko   +2 more
doaj   +1 more source

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