Results 71 to 80 of about 822,971 (295)

The Perspective Matters! Multisensory Integration in Ego-Centric Reference Frames Determines Full-Body Ownership [PDF]

, 2011
Recent advances in experimental science have made it possible to investigate the perceptual processes involved in generating a sense of owning an entire body. This is achieved by full-body ownership illusions which make use of specific patterns of visual
Valeria I. Petkova, Mehrnoush Khoshnevis, H. Henrik Ehrsson   +2 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Induced illusory body ownership in borderline personality disorder. [PDF]

Neurosci Conscious, 2019
AbstractBackgroundOne aspect of selfhood that may have relevance for Borderline Personality Disorder (BPD) is variation in sense of body ownership. We employed the rubber hand illusion (RHI) to manipulate sense of body ownership in BPD. We extended previous research on illusory body ownership in BPD by testing: 1) two illusion conditions: asynchronous &
Neustadter ES, Fineberg SK, Leavitt J, Carr MM, Corlett PR.   +4 more
europepmc   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Case Series Clinical Trial of a Novel Approach Using Augmented Reality That Inspires Self-body Cognition in Patients With Stroke: Effects on Motor Function and Resting-State Brain Functional Connectivity

Frontiers in Systems Neuroscience, 2019
Barring a few studies, there are not enough established treatments to improve upper limb motor function in patients with severe impairments due to chronic stroke.
Fuminari Kaneko, Fuminari Kaneko, Keiichiro Shindo, Keiichiro Shindo, Masaki Yoneta, Masaki Yoneta, Masaki Yoneta, Megumi Okawada, Megumi Okawada, Megumi Okawada, Kazuto Akaboshi, Kazuto Akaboshi, Kazuto Akaboshi, Meigen Liu   +13 more
doaj   +1 more source

Multisensory mechanisms of body ownership and self-location [PDF]

, 2016
Having an accurate sense of the spatial boundaries of the body is a prerequisite for interacting with the environment and is thus essential for the survival of any organism with a central nervous system.
Guterstam, Arvid
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Grasping the concept of personal property. [PDF]

, 2011
The concept of property is integral to personal and societal development, yet understanding of the cognitive basis of ownership is limited. Objects are the most basic form of property, so our physical interactions with owned objects may elucidate nuanced
Bayliss, Andrew P, Constable, Merryn D, Kritikos, Ada   +2 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source