Results 1 to 10 of about 20,397 (284)
Direct analysis of transcription factor protected cfDNA in plasma by ChIP-seq: measurement of altered CTCF binding in cancer is a novel biomarker for liquid biopsy [PDF]
Clinical EpigeneticsBackground The aggregate presence of cell free CTCF-DNA (cfCTCF-DNA) nucleoproteins in plasma has been reported. But the occupancy of individual CTCF binding sites in plasma cfCTCF-DNA has not been studied.
Dorian Pamart +9 more
doaj +2 more sources
Evaluation of plasma nucleosome concentrations and the effect of pre-analytical variables in healthy cats [PDF]
BMC Veterinary ResearchBackground Nucleosome levels have been shown to increase in dogs and humans in certain disease states, as a result of cell apoptosis, raising interest in their utility as a biomarker.
Emily Westerback +6 more
doaj +2 more sources
Open Journal of Occupational Therapy, 2015 Evidence suggests that pediatric occupational therapists predominantly use bottom-up, impairment-focused theoretical frameworks and assessments to guide their practice, despite the current trends promoting topdown, occupation-based approaches ...
Anne Kiraly-Alvarez
doaj +4 more sources
Correction: Cytokine-induced chromatin accessibility in whole blood neutrophils links to sepsis transcriptional states [PDF]
Frontiers in ImmunologyJustin Cayford +6 more
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Imagining Oneself as Forming a Whole with Others: Descartes’s View of Love
Journal of Modern Philosophy, 2021 In this paper, I address two widespread misconceptions about Descartes’s theory of love. Descartes defines love as a passion that ‘incites [the soul] to join in volition to the objects that appear to be suitable to it’ (AT XI: 387/Voss: 62).
Melanie Tate
doaj +4 more sources
Scientific Reports, 2023 During cell death, nucleosomes, the basic structural unit of chromatin, are released into the blood stream and elevated levels have been found in the plasma of patients with solid cancers.
Priscilla Van den Ackerveken +6 more
doaj +1 more source
A novel proteomics approach to epigenetic profiling of circulating nucleosomes
Scientific Reports, 2021 Alteration of epigenetic modifications plays an important role in human cancer. Notably, the dysregulation of histone post-translational modifications (PTMs) has been associated with several cancers including colorectal cancer (CRC).
Priscilla Van den Ackerveken +6 more
doaj +1 more source
BMC Veterinary Research, 2022 Background Cell free DNA, in the form of nucleosomes, is released into circulation during apoptosis and necrosis in a variety of diseases. They are small fragments of chromosomes that are composed of DNA wrapped around a histone core made of four ...
H. M. Wilson-Robles +8 more
doaj +1 more source
Experimental Brain Research, 2013 Neurological disorders of volition may be characterized by deficits in willing and/or agency. When we move our bodies through space, it is the sense that we intended to move (willing) and that our actions were a consequence of this intention (self-agency) that gives us the sense of voluntariness and a general feeling of being "in control." While it is ...
Sarah M, Kranick, Mark, Hallett
openaire +2 more sources
Characterizing circulating nucleosomes in the plasma of dogs with hemangiosarcoma
BMC Veterinary Research, 2021 Background Nucleosomes consist of DNA wrapped around a histone octamer core like thread on a spool to condense DNA as chromatin into chromosomes.
Heather Wilson-Robles +6 more
doaj +1 more source