Results 41 to 50 of about 20,397 (284)

Chromatin changes associated with neutrophil extracellular trap formation in whole blood reflect complex immune signaling

Frontiers in Immunology
BackgroundNeutrophils are key players in innate immunity, forming neutrophil extracellular traps (NETs) to defend against infections. However, excess NET formation is implicated in inflammatory conditions such as sepsis and immunothrombosis. Studying NET
Justin Cayford, Brandi Atteberry, Akanksha Singh-Taylor, Andrew Retter, Andrew Retter, Andrew Retter, Benjamin P. Berman, Benjamin P. Berman, Theresa K. Kelly   +8 more
doaj   +1 more source

Operant Variability and the Evolution of Volition [PDF]

, 2014
Volition has been debated for thousands of years:  what is it, how is it possible for biophysical beings to behave in a voluntary manner, indeed, does volition exist?  Evolution of volition has rarely been part of the discussion.
Neuringer, Allen, Neuringer, Allen,
core   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Understanding the complex chromatin dynamics in primary human neutrophils during PMA-induced NET formation

Frontiers in Immunology
BackgroundPrimary human neutrophils play a pivotal role in innate immunity, mainly through the formation of neutrophil extracellular traps (NETs) in a process known as NETosis.
Brandi Atteberry, Benjamin P. Berman, Benjamin P. Berman, Theresa K. Kelly, Justin Cayford   +4 more
doaj   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Generative Artificial Intelligence Utilization and Perspectives Among Reproductive‐Age Women With Systemic Autoimmune and Rheumatic Diseases

Arthritis Care &Research, EarlyView.
Objective Reproductive‐age women with systemic autoimmune and rheumatic diseases (SARDs) have unique information needs related to their SARDs and reproductive health. We sought to understand their use of and receptivity to current and hypothetical generative artificial intelligence (AI) tools for health information‐seeking. Methods We conducted a cross‐
Mariam Arif, Catherine Wright, Samantha Rodriguez, Sarah Graves, Tamar Krishnamurti, Mehret Birru Talabi   +5 more
wiley   +1 more source

Der Wille und das Wollen, Volition und Kovolition – Überlegungen, Konzepte und Perspektiven aus Sicht der Integrativen Therapie

, 2003
Das Willensthema hat in der Psychotherapie eine Zeit der weitgehenden Nichtbeachtung durchlaufen, und das hat komplexe Hintergründe. In allen „Schulen“ gibt es kaum Publikationen zu diesem Thema.Die Werke von Otto Rank, Rolo May, Roberto Assagioli sind ...
Petzold, Hilarion G., Sieper, Johanna
core   +1 more source

The association of gout flare resolution with physical activity and sleep: a prospective remote‐monitoring study

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to determine whether gout flare resolution is associated with physical activity and sleep. These findings were intended to inform the future development of a definition for flare resolution. Methods Data from 81 participants with gout who experienced >1 flare during a 6‐month prospective observational study were included ...
Sarah Stewart, Boston Girven, Mia Clarke, Irene Zeng, Angelo Gaffo, Lisa K Stamp, N Lawrence Edwards, David Rice, Tania Ka'ai, Karl Rudolph, Julie Collis, Nicola Kayes, Nicola Dalbeth   +12 more
wiley   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Relationship of volitional regulation and lifestyle of Tuva residents living in rural vs urban areas

Теоретическая и экспериментальная психология, 2023
Background. The paper presents the results of research into the features of volitional regulation among Tuvans living in rural areas and cities. Objectives. The study had its purpose to test the hypothesis about the relationship of volitional regulation
Vladimir N. Shlyapnikov
doaj   +1 more source