Results 1 to 10 of about 16,143 (202)
Vital NETosis vs. suicidal NETosis during normal pregnancy and preeclampsia [PDF]
Frontiers in Cell and Developmental Biology, 2023 Background: NETosis occurs in the context of infection or inflammation and results in the expulsion of decondensed DNA filaments called NETs (Neutrophil Extracellular Traps) into the extracellular environment.
Florence Guillotin +19 more
doaj +3 more sources
Molecular mechanisms and therapeutic target of NETosis in diseases
MedComm, 2022 Evidence shows that neutrophils can protect the host against pathogens in multiple ways, including the formation and release of neutrophil extracellular traps (NETs).
Mei-Hua Wan, Limin Zheng, Weiqi Hong
exaly +2 more sources
A brief report: absence of elevated circulating NETosis markers in long-term long COVID [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundNeutrophil extracellular trap (NET) formation (NETosis) has been proposed as a contributor to the pathophysiology of Long COVID (LC). However, it remains unclear whether markers of systemic NETosis remain elevated in individuals with persistent
Bart Humer +7 more
doaj +2 more sources
Netosis in the pathogenesis of antiphospholipid syndrome and systemic lupus erythematosus
Современная ревматология, 2021 Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are autoimmune diseases. In recent years, APS has been considered as an autoimmune thrombo-inflammatory disease.
K. S. Nurbaeva +2 more
doaj +1 more source
Effect of Adhesion and Substrate Elasticity on Neutrophil Extracellular Trap Formation
Frontiers in Immunology, 2019 Neutrophils are the most abundant type of white blood cells. Upon stimulation, they are able to decondense and release their chromatin as neutrophil extracellular traps (NETs). This process (NETosis) is part of immune defense mechanisms but also plays an
Luise Erpenbeck +12 more
doaj +1 more source
Experimental Gerontology, 2023 Neutrophil extracellular trap formation (NETosis) is a mechanism used by neutrophils to capture pathogens with their own DNA. However, the exacerbation of this immune response is related to serious inflammatory diseases.
Nicolás Vidal-Seguel +12 more
doaj +1 more source
Journal of Biomedical Science, 2020 Background Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory form of arthritis in which tumor necrosis factor (TNF)-α, a potent inducer of inflammatory response and a key regulator of innate immunity and of Th1 immune responses ...
Patricia Ruiz-Limon +14 more
doaj +1 more source
ROS and DNA repair in spontaneous versus agonist-induced NETosis: Context matters
Frontiers in Immunology, 2022 Reactive oxygen species (ROS) is essential for neutrophil extracellular trap formation (NETosis). Nevertheless, how ROS induces NETosis at baseline and during neutrophil activation is unknown. Although neutrophils carry DNA transcription, replication and
Dhia Azzouz +4 more
doaj +1 more source
Histone Acetylation Promotes Neutrophil Extracellular Trap Formation
Biomolecules, 2019 Neutrophils undergo a unique form of cell death to generate neutrophil extracellular traps (NETs). It is well established that citrullination of histones (e.g., CitH3) facilitates chromatin decondensation during NET formation (NETosis), particularly ...
Hussein J. Hamam +2 more
doaj +1 more source
Frontiers in Immunology, 2018 Tonicity of saline (NaCl) is important in regulating cellular functions and homeostasis. Hypertonic saline is administered to treat many inflammatory diseases, including cystic fibrosis.
Ajantha Nadesalingam +5 more
doaj +1 more source