Results 1 to 10 of about 399,078 (208)
ROS Signaling and NADPH Oxidase in Red Algae [PDF]
AntioxidantsWe explore the diverse roles of reactive oxygen species (ROS) and NADPH oxidases in red algae, focusing on their involvement in fertilization, wound repair, stress adaptation, and development.
Gwang-Hoon Kim +2 more
doaj +2 more sources
Redox Biology, 2019 The activation of NADPH oxidase contributes to dopaminergic neurodegeneration and motor deficits in Parkinson's disease (PD). However, whether NADPH oxidase is involved in non-motor symptoms, especially cognitive dysfunction in PD remains unknown.
Liyan Hou +5 more
doaj +2 more sources
eLife, 2017 Transient increases in mitochondrially-derived reactive oxygen species (ROS) activate an adaptive stress response to promote longevity. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases produce ROS locally in response to various stimuli, and ...
Collin Yvès Ewald +8 more
doaj +2 more sources
A role for NADPH oxidase in antigen presentation [PDF]
Frontiers in Immunology, 2013 The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase expressed in phagocytes is a multi-subunit enzyme complex that generates superoxide (O2.-).
Gail J Gardiner +5 more
doaj +3 more sources
NADPH oxidase-dependent production of reactive oxygen species induces endoplasmatic reticulum stress in neutrophil-like HL60 cells. [PDF]
PLoS ONE, 2015 Reactive oxygen species (ROS) primarily produced via NADPH oxidase play an important role for killing microorganisms in neutrophils. In this study we examined if ROS production in Human promyelocytic leukemia cells (HL60) differentiated into neutrophil ...
Wilson Mitsuo Tatagiba Kuwabara +5 more
doaj +2 more sources
NoxO1 Determines the Level of ROS Formation by the Nox1-Centered NADPH Oxidase [PDF]
AntioxidantsThe Nox1-centered NADPH oxidase complex facilitates the transfer of electrons from intracellular NADPH across the cell membrane to extracellular molecular oxygen, resulting in the formation of superoxide.
Dana Maureen Hebchen +3 more
doaj +2 more sources
Oxidative Medicine and Cellular Longevity, 2021 NADPH oxidase as an important source of intracellular reactive oxygen species (ROS) has gained enormous importance over the years, and the detailed structures of all the isoenzymes of the NADPH oxidase family and their regulation have been well explored.
Upasana Ganguly +6 more
semanticscholar +1 more source
NADPH Oxidase and Neurodegeneration [PDF]
Current Neuropharmacology, 2012 NADPH oxidase (Nox) is a unique, multi-protein, electron transport system that produces large amounts of superoxide via the reduction of molecular oxygen. Nox-derived reactive oxygen species (ROS) are known to be involved in a variety of physiological processes, including host defense and signal transduction.
Hernandes, Marina S, Britto, Luiz R G
openaire +2 more sources
Myeloid-derived suppressor cells modulate immune responses independently of NADPH oxidase in the ovarian tumor microenvironment in mice. [PDF]
PLoS ONE, 2013 The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses.
Heidi E Godoy +10 more
doaj +1 more source
NADPH oxidase limits innate immune responses in the lungs in mice. [PDF]
PLoS ONE, 2010 Chronic granulomatous disease (CGD), an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide anion and downstream reactive oxidant intermediates (ROIs), is characterized by recurrent bacterial and fungal ...
Brahm H Segal +20 more
doaj +1 more source