Results 11 to 20 of about 180,191 (302)
Expression and modulation of an NADPH oxidase in mammalian astrocytes [PDF]
, 2005 Amyloid β peptides generate oxidative stress in hippocampal astrocytes through a mechanism sensitive to inhibitors of the NADPH oxidase [diphenylene iodonium (DPI) and apocynin].
Abramov, A.Y. +5 more
core +1 more source
NADPH Oxidase and Neurodegeneration [PDF]
Current Neuropharmacology, 2012 NADPH oxidase (Nox) is a unique, multi-protein, electron transport system that produces large amounts of superoxide via the reduction of molecular oxygen. Nox-derived reactive oxygen species (ROS) are known to be involved in a variety of physiological processes, including host defense and signal transduction.
Hernandes, Marina S, Britto, Luiz R G
openaire +2 more sources
A role for NADPH oxidase in antigen presentation
Frontiers in Immunology, 2013 The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase expressed in phagocytes is a multi-subunit enzyme complex that generates superoxide (O2.-).
Gail J Gardiner +5 more
doaj +1 more source
Redox modulation of FAK controls melanoma survival--role of NOX4. [PDF]
PLoS ONE, 2014 Studies have demonstrated that reactive oxygen species (ROS) generated by NADPH oxidase are essential for melanoma proliferation and survival. However, the mechanisms by which NADPH oxidase regulates these effects are still unclear.
Cristiane Ribeiro-Pereira +5 more
doaj +1 more source
Phagocytic NADPH oxidase-dependent superoxide production stimulates matrix metalloproteinase-9: implications for human atherosclerosis [PDF]
, 2007 OBJECTIVE: Data suggest that matrix metalloproteinase-9 (MMP-9) has a role in atherosclerosis. The phagocytic NADPH oxidase has been also associated with atherosclerosis. This study aimed to investigate the association between phagocytic NADPH oxidase
Beloqui, O. (Óscar) +9 more
core +1 more source
Acta Societatis Botanicorum Poloniae, 2017 Cadmium-induced oxidative burst is partially mediated by NADPH oxidase. The aim of the present research was to evaluate the role of NADPH oxidase in soybeans’ response to short-term cadmium stress.
Jagna Chmielowska-Bąk +6 more
doaj +1 more source
Effects of Iodonium Analogs on Nadph Oxidase 1 in Human Colon Cancer Cells
Antioxidants, 2021 Recent studies suggest that of the molecules postulated to function as inhibitors of the NADPH oxidase family of enzymes iodonium analogs known to broadly interfere with flavin dehydrogenase function demonstrate mechanistic validity as NADPH oxidase ...
Krishnendu K. Roy +2 more
doaj +1 more source
Glycosylation with O-linked β-N-acetylglucosamine (O-GlcNAc) induces vascular dysfunction via production of superoxide anion/reactive oxygen species [PDF]
, 2018 Overproduction of superoxide anion (•O2-) and O-linked β-N-acetylglucosamine (O-GlcNAc)-modification in the vascular system are contributors to endothelial dysfunction.
Alves-Lopes, Rhéure +8 more
core +2 more sources
NADPH Oxidases in Vascular Pathology [PDF]
Antioxidants & Redox Signaling, 2014 Reactive oxygen species (ROS) play a critical role in vascular disease. While there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases play a central role. They are a source of "kindling radicals," which affect other enzymes, such as nitric oxide synthase endothelial nitric oxide synthase or xanthine oxidase.
Anna, Konior +3 more
openaire +3 more sources
Regulation of Plant NADPH Oxidase [PDF]
Plant Signaling & Behavior, 2007 The production of Reactive Oxygen Species (ROS) is one of the key events occurring during the response of plants to environmental changes, and contributing to establish adaptive signaling pathways. A plasma membrane bound NADPH oxidase enzyme has been evidenced as the ROS producing system in various plant-microorganisms interactions.
Elmayan, Taline, Simon-Plas, Françoise
openaire +3 more sources