Results 11 to 20 of about 12,736 (166)
Scavenging of Isolevuglandins Attenuates Neutrophil Migration and Neutrophil Extracellular Trap Formation in Systemic Lupus Erythematosus. [PDF]
ACR Open RheumatolObjective Systemic lupus erythematosus (SLE) is an autoimmune disease that affects numerous organs. Neutrophil extracellular traps (NETs) contribute to sterile inflammation and autoantibody generation in SLE.
Krishnan J +7 more
europepmc +2 more sources
PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury. [PDF]
Adv Sci (Weinh)Myocardial ischemia‐reperfusion (MI/R) injury remains a critical challenge in cardiovascular therapeutics, with metabolic‐inflammatory signaling axis emerging as a critical mediator of pathological outcomes. Yet, the specific metabolic pathways interplay
Wu J +11 more
europepmc +2 more sources
Netosis in the pathogenesis of antiphospholipid syndrome and systemic lupus erythematosus
Современная ревматология, 2021 Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are autoimmune diseases. In recent years, APS has been considered as an autoimmune thrombo-inflammatory disease.
K. S. Nurbaeva +2 more
doaj +1 more source
Effect of Adhesion and Substrate Elasticity on Neutrophil Extracellular Trap Formation
Frontiers in Immunology, 2019 Neutrophils are the most abundant type of white blood cells. Upon stimulation, they are able to decondense and release their chromatin as neutrophil extracellular traps (NETs). This process (NETosis) is part of immune defense mechanisms but also plays an
Luise Erpenbeck +12 more
doaj +1 more source
Histone Acetylation Promotes Neutrophil Extracellular Trap Formation
Biomolecules, 2019 Neutrophils undergo a unique form of cell death to generate neutrophil extracellular traps (NETs). It is well established that citrullination of histones (e.g., CitH3) facilitates chromatin decondensation during NET formation (NETosis), particularly ...
Hussein J. Hamam +2 more
doaj +1 more source
Experimental Gerontology, 2023 Neutrophil extracellular trap formation (NETosis) is a mechanism used by neutrophils to capture pathogens with their own DNA. However, the exacerbation of this immune response is related to serious inflammatory diseases.
Nicolás Vidal-Seguel +12 more
doaj +1 more source
Frontiers in Immunology, 2018 Tonicity of saline (NaCl) is important in regulating cellular functions and homeostasis. Hypertonic saline is administered to treat many inflammatory diseases, including cystic fibrosis.
Ajantha Nadesalingam +5 more
doaj +1 more source
Frontiers in Immunology, 2023 Reactive oxygen species (ROS) is essential for neutrophil extracellular trap formation (NETosis), and generated either by NADPH oxidases (e.g., during infections) or mitochondria (e.g., sterile injury) in neutrophils. We recently showed that ultraviolet (
Dhia Azzouz +4 more
doaj +1 more source
ROS and DNA repair in spontaneous versus agonist-induced NETosis: Context matters
Frontiers in Immunology, 2022 Reactive oxygen species (ROS) is essential for neutrophil extracellular trap formation (NETosis). Nevertheless, how ROS induces NETosis at baseline and during neutrophil activation is unknown. Although neutrophils carry DNA transcription, replication and
Dhia Azzouz +4 more
doaj +1 more source
Journal of Biomedical Science, 2020 Background Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory form of arthritis in which tumor necrosis factor (TNF)-α, a potent inducer of inflammatory response and a key regulator of innate immunity and of Th1 immune responses ...
Patricia Ruiz-Limon +14 more
doaj +1 more source