Results 41 to 50 of about 16,413 (245)

Influences of chloride and hypochlorite on neutrophil extracellular trap formation. [PDF]

PLoS ONE, 2012
The release by neutrophils of DNA-based extracellular traps (NETs) is a recently recognized innate immune phenomenon that contributes significantly to control of bacterial pathogens at tissue foci of infection.
Kathryn Akong-Moore, Ohn A Chow, Maren von Köckritz-Blickwede, Victor Nizet   +3 more
doaj   +1 more source

NETosis: A key player in autoimmunity, COVID-19, and long COVID

Journal of Translational Autoimmunity
NETosis, the process through which neutrophils release neutrophil extracellular traps (NETs), has emerged as a crucial mechanism in host defense and the pathogenesis of autoimmune responses.
D. Monsalve, Y. Acosta-Ampudia, Nicolás Guerrero Acosta, Mariana Celis-Andrade, A. Şahin, Ahsen Morva Yilmaz, Y. Shoenfeld, C. Ramírez-Santana   +7 more
semanticscholar   +1 more source

NETosis as Source of Autoantigens in Rheumatoid Arthritis [PDF]

Frontiers in Immunology, 2016
In neutrophils (but also in eosinophils and in mast cells), different inflammatory stimuli induce histone deimination, chromatin decondensation, and NET formation. These web-like structures that trap and kill microbes contain DNA, cationic granule proteins, and antimicrobial peptides, but the most abundant proteins are core histones. Histones contained
Corsiero, Elisa, PRATESI, FEDERICO, Prediletto, Edoardo, Bombardieri, Michele, MIGLIORINI, PAOLA   +4 more
openaire   +4 more sources

Functional Verification and Prognostic Value of Neutrophil Extracellular Trap-Related Genes in Pancreatic Cancer Progression

Frontiers in Bioscience-Landmark
Background: Pancreatic carcinoma (PC), a severely malignant neoplasm of the digestive system, is characterized by an unfavorable prognosis.
Jiaxin Xu, Liying Tu, Lijing Ma, Qisheng Tang, Yu Cao, Lihong Jiang   +5 more
doaj   +1 more source

CitH3, a Druggable Biomarker for Human Diseases Associated with Acute NETosis and Chronic Immune Dysfunction

Pharmaceutics
Neutrophils are essential components of innate immunity, executing a range of effector functions including phagocytosis, degranulation, and the release of neutrophil extracellular traps (NETs).
Yuchen Chen, Zoe Tetz, Xindi Zeng, S. Go, Wenlu Ouyang, Kyung Eun Lee, Tao Dong, Yongqing Li, Jianjie Ma   +8 more
semanticscholar   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

In vitro study: HIF-1α-dependent glycolysis enhances NETosis in hypoxic conditions

Frontiers in Immunology
Background Hypoxia plays a pivotal role in modulating immune responses, especially in neutrophils, which are essential components of the innate immune system.
Yi Ye, Yanjun Wang, Qiying Xu, Juanli Liu, Ziqi Yang, Tana Wuren, Ri-li Ge   +6 more
semanticscholar   +1 more source

Lonicera japonica‐Derived Nanovesicles Ameliorate Acute Lung Injury by Suppressing Neutrophil Extracellular Traps Formation in Mice

Advanced Healthcare Materials, EarlyView.
(A) Isolation and purification of LDNVs. (B) Establishment of the ALI model and LDNVs delivery. (C) Therapeutic mechanisms of LDNVs in treating ALI. This scheme figure was drawn by Figdraw, ID: IUIIO21222. ABSTRACT Acute lung injury (ALI) is a lethal respiratory disease.
Xi Lin, Jian Lin, Yezi Zhang, Xinyan Zhang, Xinghua Liu, Hongying Cao, Huan Shen, Jianming Liang, Zhenhua Dai, Siyuan Xu, Xingdong Lin   +10 more
wiley   +1 more source

Furanoid F-Acid F6 Uniquely Induces NETosis Compared to C16 and C18 Fatty Acids in Human Neutrophils

Biomolecules, 2018
Various biomolecules induce neutrophil extracellular trap (NET) formation or NETosis. However, the effect of fatty acids on NETosis has not been clearly established. In this study, we focused on the NETosis-inducing ability of several lipid molecules. We
Meraj A. Khan, Cecil Pace-Asciak, Jassim M. Al-Hassan, Mohammad Afzal, Yuan Fang Liu, Sosamma Oommen, Bincy M. Paul, Divya Nair, Nades Palaniyar   +8 more
doaj   +1 more source

IL‐7R‐Enriched Extracellular Vesicles From the Thymus Drive Colitis via Promoting Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao, Yuheng Liu, Ruibing Yang, Zifeng Zhu, Junwei Wu, Dinghao Li, Jin Su, Yingxin He, Shiqi Luo, Feiyang Cao, Haiyi Deng, Lanmengxi Yang, Ling Zhong, Peiying Peng, Xinyi Wu, Chunmei Cai, Zhen Li, Yujin Wu, Shuofeng Zhu, Jie Wei, Yi Yang, Lifu Wang   +21 more
wiley   +1 more source