Results 131 to 140 of about 740,807 (259)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Preservation of Traumatic Completely Amputated or Avulsed Body Parts in the First Aid Setting: A Scoping Review. [PDF]

Cureus
Singletary E, Laermans J, Pek JH, Cassan P, Meyran D, Berry D, Thilakasiri K, Djarv T.   +7 more
europepmc   +1 more source

Gaze-cued shifts of attention and microsaccades are sustained for whole bodies but are transient for body parts. [PDF]

Psychon Bull Rev, 2022
Han NX, Eckstein MP.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Fading Roars? A Survey of the Cultural Use and Illegal Trade in Wild Felid Body Parts in Côte d'Ivoire. [PDF]

Animals (Basel)
Horion R, Aglissi J, Pickles R, Ouattara A, Drouilly M.   +4 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Laws about bodily damage originate from shared intuitions about the value of body parts. [PDF]

Sci Adv
Wee YN, Sznycer D, Krems JA.
europepmc   +1 more source

Does the body talk to the body? The relationship between different body representations while observing others' body parts. [PDF]

Br J Psychol, 2022
Tessari A, Ottoboni G.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Intracortical recordings reveal the neuronal selectivity for bodies and body parts in the human visual cortex. [PDF]

Proc Natl Acad Sci U S A
Ramirez JG, Vanhoyland M, Ratan Murty NA, Decramer T, Van Paesschen W, Bracci S, Op de Beeck H, Kanwisher N, Janssen P, Theys T.   +9 more
europepmc   +1 more source