Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Workers' Injury Risks Focusing on Body Parts in Reinforced Concrete Construction Projects. [PDF]
Lim J, Cho J, Kim J, Kang S.
europepmc +1 more source
Effect of cold ambient temperature on heat flux, skin temperature, and thermal sensation at different body parts in elite biathletes. [PDF]
Blokker T +3 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Scaling Relationships and Sexual Size Dimorphism Among the Body Parts of <i>Holotrichia oblita</i> (Coleoptera: Scarabaeidae). [PDF]
Zhu M +5 more
europepmc +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Comparative analysis of skin transcriptome reveals differences of cashmere fineness in different body parts of Inner Mongolia cashmere goats. [PDF]
Zhou B +8 more
europepmc +1 more source
Kimura's disease successively affecting multiple body parts: a case-based literature review. [PDF]
Yang B +7 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Preservation of Traumatic Completely Amputated or Avulsed Body Parts in the First Aid Setting: A Scoping Review. [PDF]
Singletary E +7 more
europepmc +1 more source

