Results 51 to 60 of about 185,748 (298)
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
BMP Signaling: Lighting up the Way for Embryonic Dorsoventral Patterning
Frontiers in Cell and Developmental Biology, 2021 One of the most significant events during early embryonic development is the establishment of a basic embryonic body plan, which is defined by anteroposterior, dorsoventral (DV), and left-right axes.
Yifang Yan +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Reorganization of mammalian body wall patterning with cloacal septation
Scientific Reports, 2017 Septation of the cloaca is a unique mammalian adaptation that required a novel reorganization of the perineum–the caudal portion of the trunk body wall not associated with the hindlimb.
Margaret I. Hall +2 more
doaj +1 more source
Conservation and co-option in developmental programmes: the importance of homology relationships [PDF]
, 2005 One of the surprising insights gained from research in evolutionary developmental biology (evo-devo) is that increasing diversity in body plans and morphology in organisms across animal phyla are not reflected in similarly dramatic changes at the level ...
Becker, May-Britt +3 more
core +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source
Impact of resistant starch on body fat patterning and central appetite regulation.
PLoS ONE, 2007 BackgroundAdipose tissue patterning has a major influence on the risk of developing chronic disease. Environmental influences on both body fat patterning and appetite regulation are not fully understood. This study was performed to investigate the impact
Po-Wah So +6 more
doaj +1 more source
Pattern regulation in a regenerating jellyfish
eLife, 2020 Jellyfish, with their tetraradial symmetry, offer a novel paradigm for addressing patterning mechanisms during regeneration. Here we show that an interplay between mechanical forces, cell migration and proliferation allows jellyfish fragments to regain ...
Chiara Sinigaglia +7 more
doaj +1 more source
Daily rhythmic behaviors and thermoregulatory patterns are disrupted in adult female MeCP2-deficient mice. [PDF]
PLoS ONE, 2012 Mutations in the X-linked gene encoding Methyl-CpG-binding protein 2 (MECP2) have been associated with neurodevelopmental and neuropsychiatric disorders including Rett Syndrome, X-linked mental retardation syndrome, severe neonatal encephalopathy, and ...
Robert G Wither +5 more
doaj +1 more source
Ancient Pbx-Hox signatures define hundreds of vertebrate developmental enhancers [PDF]
, 2011 Background: Gene regulation through cis-regulatory elements plays a crucial role in development and disease. A major aim of the post-genomic era is to be able to read the function of cis-regulatory elements through scrutiny of their DNA sequence ...
Bronner, Marianne E. +4 more
core +5 more sources