Results 71 to 80 of about 185,748 (298)

The TALE face of Hox proteins in animal evolution

Frontiers in Genetics, 2015
Hox genes are major regulators of embryonic development. One of their most conserved functions is to coordinate the formation of specific body structures along the anterior-posterior (AP) axis in Bilateria.
Samir eMerabet, Brigitte eGalliot
doaj   +1 more source

The last common bilaterian ancestor [PDF]

, 2002
Many regulatory genes appear to be utilized in at least superficially similar ways in the development of particular body parts in Drosophila and in chordates.
Davidson, Eric H., Erwin, Douglas H.
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Microheated substrates for patterning cells and controlling development

, 2005
Here, we seek to control cellular development by devising a means through which cells can be subjected to a microheated environment in standard culture conditions.
Everett, W.N., Liu, M.H.H., Ma, Y.X., Moran, P.M., Shu, W.M., Spearing, S.M., Sue, H.J., Trigg, A., Wang, S., Zhang, Q.X.   +9 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Antero-posterior patterning in the brittle star Amphipholis squamata and the evolution of echinoderm body plans

EvoDevo
Although the adult pentaradial body plan of echinoderms evolved from a bilateral ancestor, identifying axial homologies between the morphologically divergent echinoderms and their bilaterian relatives has been an enduring problem in zoology.
L. Formery, P. Peluso, D. R. Rank, D. S. Rokhsar, C. J. Lowe   +4 more
doaj   +1 more source

Uncoupling of complex regulatory patterning during evolution of larval development in echinoderms

BMC Biology, 2010
Background Conservation of orthologous regulatory gene expression domains, especially along the neuroectodermal anterior-posterior axis, in animals as disparate as flies and vertebrates suggests that common patterning mechanisms have been conserved since
Jennings Charlotte K, Martik Megan L, Yankura Kristen A, Hinman Veronica F   +3 more
doaj   +1 more source

Sexual signaling pattern correlates with habitat pattern in visually ornamented fishes

Nature Communications, 2020
Sensory drive theory posits that selection on sexual signals should depend on the environmental background. Here, Hulse et al. analyze the spatial statistics of body patterning in 10 darter fish species and find a correlation with habitat spatial ...
Samuel V. Hulse, Julien P. Renoult, Tamra C. Mendelson   +2 more
doaj   +1 more source