Results 61 to 70 of about 448,440 (292)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

IMPROVING DRAW-A-PERSON TEST RESULTS BY DEVELOPING THE BODY SCHEMA DURING PHYSICAL EDUCATION AND SPORT LESSONS FOR STUDENTS AGED 6-7 YEARS

open access: yesStudia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae, 2022
Introduction: The physical education lesson in primary school can make an essential contribution to the psychomotor development of students. The purpose of this study is to highlight the progress made in the development of the Body Schema following the ...
Cristina SUNEI   +2 more
doaj   +1 more source

A Review of Shaun Gallagher: How the Body Shapes the Mind [PDF]

open access: yes, 2006
With 'How the body shapes the mind', Shaun Gallagher provides a general panoptic of the importance of the body in cognition, based on significant experimental results.
De Vignemont, Frédérique
core   +1 more source

Distribution Constraints: The Chase for Distributed Data [PDF]

open access: yes, 2020
This paper introduces a declarative framework to specify and reason about distributions of data over computing nodes in a distributed setting. More specifically, it proposes distribution constraints which are tuple and equality generating dependencies ...
Geck, Gaetano   +2 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Tool use induces complex and flexible plasticity of human body representations [PDF]

open access: yes, 2012
Plasticity of body representation fundamentally underpins human tool use. Recent studies have demonstrated remarkably complex plasticity of body representation in humans, showing that such plasticity: (1) occurs flexibly across multiple time-scales, and (
Longo, Matthew R., Serino, A.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Habit and the Extended Mind: Fleshing Out the Extended Mind Theory with Merleau-Pontian Phenomenology

open access: yesPhenomenology and Mind, 2016
This short essay attempts to flesh out the extended mind thesis by showing the nontrivial role of the body in skilled epistemic action. This is attempted by bringing Merleau-Ponty’s notion of the body schema together with Clark and Chalmers account of ...
Richard Charles Strong
doaj   +1 more source

Is it ‘me’ or is it ‘mine’? The Mycenaean sword as a body-part. [PDF]

open access: yes, 2008
This paper argues that material culture has the ability to change and shape our bodies by transforming and extending the boundaries of our body schema.
Malafouris, Dr Lambros
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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