Results 81 to 90 of about 5,186,159 (320)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Studia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae, 2022 Introduction: The physical education lesson in primary school can make an essential contribution to the psychomotor development of students. The purpose of this study is to highlight the progress made in the development of the Body Schema following the ...
Cristina SUNEI +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Phenomenology and Mind, 2016 This short essay attempts to flesh out the extended mind thesis by showing the nontrivial role of the body in skilled epistemic action. This is attempted by bringing Merleau-Ponty’s notion of the body schema together with Clark and Chalmers account of ...
Richard Charles Strong
doaj +1 more source
Semantic Query Reformulation in Social PDMS [PDF]
, 2011 We consider social peer-to-peer data management systems (PDMS), where each peer maintains both semantic mappings between its schema and some acquaintances, and social links with peer friends.
Angela Bonifati +4 more
core +1 more source
Schema Independent Relational Learning
, 2017 Learning novel concepts and relations from relational databases is an important problem with many applications in database systems and machine learning. Relational learning algorithms learn the definition of a new relation in terms of existing relations ...
Abiteboul S. +7 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Reducing Dueling Bandits to Cardinal Bandits [PDF]
, 2014 We present algorithms for reducing the Dueling Bandits problem to the conventional (stochastic) Multi-Armed Bandits problem. The Dueling Bandits problem is an online model of learning with ordinal feedback of the form "A is preferred to B" (as opposed to
Ailon, Nir +2 more
core +1 more source
The racist bodily imaginary: the image of the body-in-pieces in (post)apartheid culture [PDF]
, 2013 This paper outlines a reoccurring motif within the racist imaginary of (post)apartheid culture: the black body-in-pieces. This disturbing visual idiom is approached from three conceptual perspectives.
A Krog +34 more
core +1 more source