Results 111 to 120 of about 2,935,731 (302)

Relationship between mastitis and body condition score in jersey cattle [PDF]

open access: yesBIO Web of Conferences
The usefulness, validity and precision of the body condition score has been proven by many studies to evaluate body energy reserves. In general, the body condition score decreases in early lactation because cows allocate energy from their body reserves ...
Gökçe Gökhan, Şenses Ezgi
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Improving the clinical detection of Lewy body dementia with the Lewy body composite risk score

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2015
Introduction Dementia with Lewy bodies (DLB) is a challenge to diagnose, particularly outside of expert centers with long delays in diagnosis leading to significant burden to patients and caregivers. Although consensus criteria have excellent specificity,
James E. Galvin
doaj   +1 more source

The Finnish Diabetes Risk Score (FINDRISC) and increased body weight

open access: yesJournal of Medical Science, 2016
Introduction. The Finnish Diabetes Risk Score (FINDRISC) assesses the 10-year type 2 diabetes risk in adults by identifying individuals with overweight or obesity, inadequate physical activity, poor nutrition, or a family or personal history of ...
Joanna Pekar   +5 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Body condition score (BCS) and metabolic status of shelter dogs

open access: yesItalian Journal of Animal Science, 2010
A group of 147 shelter dogs were weighted and assigned a body condition score (BCS) using a 9 point scale system, in order to evaluate the prevalence of obesity in the kennel.
I. Andrighetto   +5 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Risk Factors of Diabetes Mellitus in Rural Puducherry [PDF]

open access: yes, 2012
Purpose: Prevalence of type 2 diabetes is increasing in India. Rural area constitutes 80% of India. Hence it is essential to understand the epidemiology for appropriate interventions.
Das, AK   +3 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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