Results 131 to 140 of about 2,935,731 (302)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The relationship between canine body condition score and hematologic profile [PDF]
Warasan Witthayasat Lae Theknoloyi Mahawitthayalai Mahasarakham, 2019 This study aims to investigate the correlation between the body condition score (BCS) and hematological profiles of stray dogs in Maha Sarakham province.
Thanaporn Asawapattanakul
doaj
How Health Claims on Product Packaging Influence Consumer Perceptions and Purchase Decisions [PDF]
, 2016 The goal of this investigation was to expand upon research from the field of consumer behavior, with a specific focus on food product packaging and health claims. It specifically focused on how these health claims impact consumer perceptions and purchase
Vanasse, Taylor
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The early socioeconomic effects of teenage childbearing [PDF]
A large body of literature has documented a negative correlation between teenage childbearing and teen mothers’ socioeconomic outcomes, yet researchers continue to disagree as to whether the association represents a true causal effect.
Dohoon Lee
core
What is the prevalence, and what are the clinical correlates, of insulin resistance in young people presenting for mental health care? A cross-sectional study [PDF]
, 2019 Objectives: To report the distribution and predictors of insulin resistance (IR) in young people presenting to primary care-based mental health services. Design: Cross-sectional.
Carpenter, Joanne S +10 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
EFFECT OF PRE-CALVING BCS ON POSTPARTUM BCS AND BODY WEIGHT CHANGE OF SAHIWAL CATTLE [PDF]
Exploratory Animal and Medical Research, 2019 A total of 18 Sahiwal cattle of 1st to 4th parity were selected for the study and distributed into three different groups based on their pre calving body condition score (BCS) (before 15 days of expected date of calving) namely G1 (2.50 - 3.00), G2 (3 ...
V. Sharma +5 more
doaj
Body Condition Scoring for Horses
, 2019 Horse enthusiasts are often concerned about their horse’s health, appearance and performance. A major key to accomplishing these three goals is to keep your horse at a desirable body condition, or degree of fat cover. However, being able to accurately evaluate a horse to tell if they are over or underweight has been a subjective practice for many years.
Hoopes, Karl +2 more
openaire +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source