Results 51 to 60 of about 2,369,761 (349)

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Effect of body mass index on pharmacokinetics of paclitaxel in patients with early breast cancer

Cancer Medicine, 2021
Background Paclitaxel is dosed according to body surface area (BSA) but there is scant information on actual drug exposure in overweight and obese patients.
Vikram Gota, Manjunath Nookala, Avinash Bonda, Ashwin Karanam, Bharati Shriyan, Yogesh Kembhavi, Murari Gurjar, Anand Patil, Ashish Singh, Navin Goyal, Sudeep Gupta   +10 more
doaj   +1 more source

Geographical altitude, size, mass and body surface area in children (1–4 years) in the Province of Jujuy (Argentina)

Annals of Human Biology, 2015
Background: Highland child populations show low growth rates. Aim: To evaluate the variation of size, mass and body surface area of Jujenean infants (1–4 years) as a function of geographic altitude.
Estela M. Román, I. Bejarano, E. Alfaro, Guadalupe Abdo, J. Dipierri   +4 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Management of an Electrocuted Burn Injury in a District Hospital-A Case Report and Literature Review [PDF]

Journal of Clinical and Diagnostic Research, 2018
Electrical burns are one of the important health burdens throughout the world with incidences varying between 4-18% of all burns. They comprise of several types, including lighting injury, high voltage injury (>1000V) and low voltage injury (
Khoo Kah Seng, Leong Qi Wen, Bustaman Syamimi, Ho Choon Aik, Lim Chen Hong   +4 more
doaj   +1 more source

Determination of Body Surface Area and Formulas to Estimate Body Surface Area Using the Alginate Method

Journal of PHYSIOLOGICAL ANTHROPOLOGY, 2008
The purpose of this study was to determine the body surface area (BSA) based on the alginate method, to derive formulae for estimating BSA, and to compare the error of the present formula to previous formulas obtained from other countries. We directly measured the entire body surface area of 34 males (20-60 years old, 158.5-187.5 cm in height, 48.5-103.
Jeong-Wha Choi, Joo-Young Lee, Ho Kim
openaire   +4 more sources

Evaluation of Five Formulae for Estimating Body Surface Area of Nigerian Children

Annals of Medical and Health Sciences Research, 2014
Background: Physiological functions are often assessed by standardizing for body surface area (BSA) to avoid excessive variation in calculations in pediatric practice.
Adebola Emmanuel Orimadegun, A.O. Omisanjo   +1 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Analysis of the mean electrical axis of the heart from standard electrographic leads in normal adult males

Journal of Karnali Academy of Health Sciences
Background: Electrocardiogram has been widely applied as a diagnostic tool for cardiovascular disease. The concept of the cardiac vector is crucial for the clinical application in ECG interpretation.
Rajesh Prajapati, Neebha Amatya, Rajab Rana Magar, Ripti Shrestha, Prakash Baral, Narayan Mahotra   +5 more
doaj   +1 more source

Lund and Browder chart—modified versus original: a comparative study [PDF]

Acute and Critical Care, 2019
Background The Lund and Browder (LB) chart is currently the most accurate and widely used chart to calculate total body surface area affected by a burn injury.
Arun Murari, Kaushal Neelam Singh
doaj   +1 more source