Results 61 to 70 of about 2,552,275 (334)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Psoriasis clearance rates with different treatments – An In-depth retrospective chart review
Journal of Dermatology and Dermatologic Surgery, 2023 Background: Before the advent of biologics, psoriasis clearance was not a realistic goal of treatment. Purpose: This retrospective chart review aimed to compare the rates of psoriasis clearance associated with different modes of therapy in real-life ...
Katie Lovell +3 more
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
International Journal of Anatomy Radiology and Surgery, 2022 Introduction: Measurement of the aortic and pulmonary valve dimensions is critical in diagnosing stenotic diseases as well as preparation of prosthetic valves.
Sandhya Rani Chatripalli +1 more
doaj +1 more source
Passive control of a falling sphere by elliptic-shaped appendages
, 2017 The majority of investigations characterizing the motion of single or multiple particles in fluid flows consider canonical body shapes, such as spheres, cylinders, discs, etc.
Bagheri, Shervin +3 more
core +1 more source
Development of an ultrasonic resonator for ballast water disinfection [PDF]
, 2016 Ultrasonic disinfection involves the application of low-frequency acoustic energy in a water body to induce cavitation. The implosion of cavitation bubbles generates high speed microjets >1 km/s, intense shock wave >1 GPa, localized hot spots > ...
Balasubramaniam, Prakash +3 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Body surface area formulae: an alarming ambiguity
Scientific Reports, 2016 AbstractBody surface area (BSA) plays a key role in several medical fields, including cancer chemotherapy, transplantology, burn treatment and toxicology. BSA is often a major factor in the determination of the course of treatment and drug dosage. A series of formulae to simplify the process have been developed.
Grzegorz Redlarski +2 more
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Hawking radiation and black hole spectroscopy in Horava-Lifshitz gravity
, 2010 Hawking radiation from the black hole in Horava-Lifshitz gravity is discussed by a reformulation of the tunneling method given in \cite{Banerjee:2008sn}.
Akhmedov +68 more
core +1 more source