Results 81 to 90 of about 3,035,966 (300)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The Effect of Virtual Fencing Stimuli on Stress Responses and Behavior in Sheep
To understand the animal welfare impact of virtual fencing stimuli (audio cue ‘beep’ and electrical stimulus) on naïve sheep, it is necessary to assess stress responses during the animal’s first encounters with these stimuli ...
Tellisa Kearton +4 more
doaj +1 more source
Conically shaped cavity radiometer with a dual purpose cone winding Patent [PDF]
Black body radiometer design with temperature sensing and cavity heat source cone ...
Kendall, J. M., Sr. +1 more
core +1 more source
Cumulant approach to the low-temperature thermodynamics of many-body systems
Current methods to describe the thermodynamic behavior of many-particle systems are often based on perturbation theory with an unperturbed system consisting of free particles.
Becker, Klaus W. +2 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Vaginal implant transmitters for continuous body temperature measurement in moose
Measuring body temperature in free‐ranging ungulates is challenging. We evaluated a vaginal implant transmitter (TVIT) modified to collect continuous body temperature of captive and wild female moose (Alces alces) in Alaska, USA.
Daniel P. Thompson +5 more
doaj +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Comparison of Effects of Isoflurane and Propofol on Body Temperature Changes during Knee Arthroscopy Surgery [PDF]
Background & Objective: Anesthesiologists are often facing patients who suffer from hypothermia during anesthesia and shivering after surgery. This study compared the effects of anesthesia with isoflurane and propofol on the intensity of body temperature
Minoo Ghahraman +2 more
doaj
This study aims to obtain the physiological value of dugongs that live in natural habitats (in-situ) as protected wildlife, namely on the coast of Lingayan Island, Toli-Toli Regency. Wild dugongs caught on the beach were put into a net cage.
Aryani Sismin Satyaningtijas +3 more
doaj +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

