Results 91 to 100 of about 1,505,822 (375)
The impacts of environmental warming on Odonata: a review [PDF]
, 2008 Climate change brings with it unprecedented rates of increase in environmental temperature, which will have major consequences for the earth's flora and fauna.Adams J., Alcamo J., Angelibert S., Aoki T., Arendt J. D., Askew R. R., Atkinson D., Balmford A., Bendell B. E., Blanckenhorn W. U., Blumenshine S. C., Boehms C., Boothby J., Boothby J., Both C., Braune E., Brown J. H., Burgmer T., Carpenter S. R., Cham S. A., Chang X., Clark T. E., Collingham Y. C., Conrad K. F., Conrad K. F., Coope G. R., Coope G. R., Coope G. R., Corbet P. S., Corbet P. S., Corbet P. S., Corbet P. S., Corbet P. S., Corbet P. S., Corbet P. S., Corbet P. S., Corbet P. S., Cordero Rivera A., Crick H. Q.P., Crowley P. H., Dale M., Danilevskii A. S., Daufresne M., Davis M. B., Dawson T. P., De Block M., De Block M., De Block M., De Block M., Dingemanse N. J., Dorn N. J., Dunn R. R., Eversham B. C., Feuchtmayr H. D., Fitter A. H., Flenner I., Grabow K., Gresens S. E., Hammond C. O., Harada T., Harrington R., Harrington R., Hassall C., Hassall C., Heino J., Henrickson B., Hickling R., Hickling R., Hilfert-Rüppell D., Hill J. K., Hitch A. T., Hostetier S. W., Hunger H., Hynes H. B.N., Ingram B. R., Ingram B. R., Jenner C. E., Johansson F., Johansson F., Karl T. R., Knight T. M., Krishnaraj R., Lawton J. H., Leggott M., Lutz P. E., Lutz P. E., Mann M. E., Masseau M. J., May M. L., May M. L., Meehl G. A., Menetrey N., Merritt R., Michiels N. K., Mooij W. M., Nicholls R. J., Nicholls R. J., Norling U., Norling U., Norling U., Opdam P., Ott J., Ott J., Ott J., Pandey J. P., Parmesan C., Parmesan C., Parmesan C., Pearce-Higgins J. W., Phillips B. L., Pickup J., Piironen J., Pilgrim J. M., Polcyn D. M., Pritchard G., Pritchard G., Pritchard G., Pritchard G., Pritchard G., Pritchard G., Purse B. V., Rantala M. J., Robb T., Robb T., Rolff J., Rouquette J. R., Roy D. B., Sawchyn W. W., Schneider C., Shennan I., Sherratt T. N., Simberloff D., Simmons A. D., Siva-Jothy M. T., Siva-Jothy M. T., Slatkin M., Soluk D. A., Sternberg K., Sternberg K., Sternberg K., Sternberg K., Suhling F., Suhling F., Thompson D. J., Thompson D. J., Thompson D. J., Thompson D. J., Thompson D. J., Travis J. M.J., Valtonen P., Van De Meutter F., Van Doorslaer W., Veron J. E.N., Walther G. R., Waringer J. A., Watanabe M., Watts P. C., Williams D. D., Winder M., Woodward G., Woodward G., Wootton R. J., Xenopoulos M. A., Xenopoulos M. A., Yourth C. P., Zwolsman J. J.G. +165 morecore +1 more sourceIn vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni +14 morewiley +1 more sourceHepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals
Molecular Metabolism, 2019 Objective: c-Jun, a prominent member of the activator protein 1 (AP-1) family, is involved in various physiology processes such as cell death and survival. However, a role of hepatic c-Jun in the whole-body metabolism is poorly understood.Fei Xiao, Yajie Guo, Jiali Deng, Feixiang Yuan, Yuzhong Xiao, Lijian Hui, Yu Li, Zhimin Hu, Yuncai Zhou, Kai Li, Xiao Han, Qichen Fang, Weiping Jia, Yan Chen, Hao Ying, Qiwei Zhai, Shanghai Chen, Feifan Guo +17 moredoaj +1 more sourceInhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge +18 morewiley +1 more sourceAggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera +11 morewiley +1 more sourceFunctional Changes Induced by Orexin A and Adiponectin on the Sympathetic/Parasympathetic Balance
Frontiers in Physiology, 2018 Obesity and lifestyle-related diseases are major problems faced by people in developed nations. Although exercise training prevents the progression of diabetes and obesity, the motivation for exercise is generally low in obese animals and humans.Antonietta Messina, Marcellino Monda, Anna Valenzano, Giovanni Messina, Ines Villano, Fiorenzo Moscatelli, Giuseppe Cibelli, Gabriella Marsala, Rita Polito, Maria Ruberto, Marco Carotenuto, Vincenzo Monda, Andrea Viggiano, Aurora Daniele, Ersilia Nigro +14 moredoaj +1 more sourceGlycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala +18 morewiley +1 more sourceAmino Acid‐Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis
Advanced ScienceAmino acid sensing in the central nervous system plays a key role in regulating energy homeostasis. The anterior piriform cortex (APC) has been implicated in sensing amino acid deficiency and rapidly inducing an aversive response.Peixiang Luo, Kexin Tong, Yeting Gan, Min Tang, Yuguo Niu, Kan Liu, Shihong Ni, Shangming Wu, Xiaoxue Jiang, Haizhou Jiang, Fei Xiao, Shanghai Chen, Wei Lv, Xiaoying Li, Feixiang Yuan, Feifan Guo +15 moredoaj +1 more source