Results 71 to 80 of about 506,669 (258)

Hypothalamus and Regulation of Body Temperature.

Experimental Biology and Medicine, 1935
Recent work1 has shown that the hypothalamus plays an important part in the regulation of body temperature.
Ranson, S. W., Ingram, W. R.
openaire   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Effect of climate on strategies of nest and body temperature regulation in paper wasps, Polistes biglumis and Polistes gallicus. [PDF]

Sci Rep, 2022
Stabentheiner A, Nagy JM, Kovac H, Käfer H, Petrocelli I, Turillazzi S.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Post-Exercise Recovery in Paralympic Athletes: A Narrative Review of Physiological Considerations and Practical Applications

Applied Sciences
Paralympic athletes are challenged by unique systemic strain due to impairment-related physiological and psychological stressors. This study aims to synthesize the current evidence regarding post-exercise recovery modalities in Paralympic athletes ...
Exal Garcia-Carrillo, Eduardo Guzmán-Muñoz, Felipe Montalva-Valenzuela, Antonio Castillo-Paredes, Yeny Concha-Cisternas, Jose Jairo Narrea Vargas, Sergio Sazo-Rodríguez, Izham Cid-Calfucura, José Francisco López-Gil   +8 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Comparing the effect of once and alternate tepid sponging with Acetaminophen on changes of body temperature of feverish children

Journal of Holistic Nursing and Midwifery, 2005
: Introduction: Fever is one of the most common reasons for referring to emergency and clinics (30% of referrals). Primary goal of treating feverish children is to prevent permanent brain and nerve tissue damages.
ezat paryad, sobhaneh kouchakzadeh talami, elham bidabadi, kolsoom fadakar, zahra atrkar roushan   +4 more
doaj  

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Skin wetness perception across body sites in children and adolescents aged 7–16 years old

Experimental Physiology
Human skin wetness perception relies on the multisensory integration of thermal and mechanical cues during contact with moisture. Yet, it is unknown whether children and adolescents perceive skin wetness similarly to younger and older adults.
Alessandro Valenza, Hannah Blount, Jade Ward, Charlotte Merrick, Riley Wootten, Jasmin Dearden, Charlotte Wildgoose, Antonino Bianco, Alex Buoite‐Stella, Victoria L. Filingeri, Peter R. Worsley, Davide Filingeri   +11 more
doaj   +1 more source