Results 271 to 280 of about 1,241,817 (374)

CRISPR/Cas9-mediated in vivo gene editing reveals that neuronal 5-HT1A receptors in the dorsal raphe nucleus contribute to body temperature regulation in mice

, 2019
Naoya Nishitani, Yu Ohmura, Kazuki Nagayasu, Norihiro Shibui, Shuji Kaneko, Akiko Ohashi, Takayuki Yoshida, Akihiro Yamanaka, Mitsuhiro Yoshioka   +8 more
openalex   +2 more sources

Switching of Magnetic Order via Non‐Magnetic Al Addition in FeCoNiMnAlx Films

Advanced Functional Materials, EarlyView.
Non‐magnetic Al addition provides a sensitive handle to switch the magnetic order in high entropy FeCoNiMnAlx thin films via fcc to bcc phase transformation. Films with fcc structure exhibit a large exchange bias, while bcc films exhibit enhanced ferromagnetic properties, reflecting the magnetic ground state of Mn which switches from antiferromagnetic ...
Willie B. Beeson, Dinesh Bista, Nushrat Naushin, Alpha T. N'Diaye, Roopali Kukreja, Gen Yin, Kai Liu   +6 more
wiley   +1 more source

Thermogenesis and Energy Metabolism in Brown Adipose Tissue in Animals Experiencing Cold Stress. [PDF]

Int J Mol Sci
Zhang X, Xiao J, Jiang M, Phillips CJC, Shi B.   +4 more
europepmc   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

Sex differences in metabolic regulation by Gi/o-coupled receptor modulation of exocytosis. [PDF]

Front Pharmacol
Young M, Ceddia RP, Thompson-Gray A, Reyes D, Cassada JB, Ayala JE, McGuinness OP, Collins S, Hamm HE.   +8 more
europepmc   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

Advanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie, Samin Abbaszadeh, Kik Marais, Vahideh Nosrati‐Siahmazgi, Saman Rezaei, Bo Xiao, Kamal Dua, Hélder A. Santos, Mohammad‐Ali Shahbazi   +8 more
wiley   +1 more source

Adaptive Thermogenesis and Lipid Metabolism Modulation in Inguinal and Perirenal Adipose Tissues of <i>Hezuo Pigs</i> in Response to Low-Temperature Exposure. [PDF]

Cells
Li Y, Shi HX, Li J, Du H, Jia R, Liang YH, Huang XY, Gao XL, Gun SB, Yang QL.   +9 more
europepmc   +1 more source

Mother–offspring conflict and body temperature regulation during gestation and lactation in a wild primate [PDF]

Richard McFarland, S. Peter Henzi, Andrea Fuller, Robyn S. Hetem, Christopher Young, Louise Barrett   +5 more
openalex   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Effects of Temperature on the Thermal Biology and Locomotor Performance of Two Sympatric Extreme Desert Lizards. [PDF]

Animals (Basel)
Zheng Y, Wu R, Wang Z, Wu X, Feng H, Yang Y.   +5 more
europepmc   +1 more source