Results 1 to 10 of about 157,059 (165)
Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity
iScience, 2023 Summary: The hypothalamus is a region of the brain that plays an important role in regulating body functions and behaviors. There is a growing interest in human pluripotent stem cells (hPSCs) for modeling diseases that affect the hypothalamus.
Lily Sarrafha +14 more
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Complex negative emotions induced by electrical stimulation of the human hypothalamus
Brain Stimulation, 2022 Background: Stimulation of the ventromedial hypothalamic region in animals has been reported to cause attack behavior labeled as sham-rage without offering information about the internal affective state of the animal being stimulated.
Josef Parvizi +13 more
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Current Biology, 2014 SummaryThe hypothalamus is one of the oldest and smallest parts of the brain, constituting just 4 gm of the 1400 gm of adult human brain weight. And yet this tiny area contains highly conserved neural circuitry that controls basic life functions: these include energy metabolism, from feeding through digestion, metabolic control, and energy expenditure;
Saper, Clifford B., Lowell, Bradford B.
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Frontiers in Neuroscience, 2021 Despite striking progress in the understanding of the neurobiology of insomnia disorder (ID), about 40% of ID patients do not reach sustained remission with the primary treatments. It is necessary to reveal novel neuroimaging biomarkers for sleep quality
Shuang Ding +6 more
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MicroRNAs in the Hypothalamus [PDF]
Neuroendocrinology, 2013 MicroRNAs (miRNAs) are short (∼22 nucleotides) non-coding ribonucleic acid (RNA) molecules that negatively regulate the expression of protein-coding genes. Posttranscriptional silencing of target genes by miRNA is initiated by binding to the 3′-untranslated regions of target mRNAs, resulting in specific cleavage and subsequent degradation of the mRNA ...
Meister, Björn +2 more
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Blooming in the Hypothalamus [PDF]
Journal of Neurosciences in Rural Practice, 2019 ABSTRACTCavernomas are vascular malformations which are collections of endothelium-lined sinusoids without intervening cerebral parenchyma. Hypothalamic location of cavernoma is extremely rare. We present a case of a 34-year-old male who presented with complaints of recent memory loss and vomiting.
Rai, Santosh P. V. +3 more
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Conserved Genoarchitecture of the Basal Hypothalamus in Zebrafish Embryos
Frontiers in Neuroanatomy, 2020 Analyses of genoarchitecture recently stimulated substantial revisions of anatomical models for the developing hypothalamus in mammalian and other vertebrate systems.
Theresa Schredelseker +3 more
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BMC Neuroscience, 2022 Background Exercise boosts the health of some brain parts, such as the hippocampus and hypothalamus. Several studies show that long-term exercise improves spatial learning and memory, enhances hypothalamic leptin sensitivity, and regulates energy balance.
Shu-Jing Liu +12 more
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Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. [PDF]
PLoS ONE, 2013 In a previous study, we provided evidence for the presence in hypothalamus and Brockmann bodies (BB) of rainbow trout Oncorhynchus mykiss of sensing systems responding to changes in levels of oleic acid (long-chain fatty acid, LCFA) or octanoic acid ...
Marta Librán-Pérez +3 more
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Neurotrauma Reports, 2023 Blast-induced traumatic brain injury (bTBI) frequently results in sleep and circadian rhythm disturbances. We have investigated whether dysregulation of circadian rhythm after bTBI is mediated by dysregulation of clock genes in the hypothalamus and ...
Manoj Govindarajulu +4 more
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