Results 21 to 30 of about 192,010 (311)

Notch signalling and proneural genes work together to control the neural building blocks for the initial scaffold in the hypothalamus

Frontiers in Neuroanatomy, 2014
The vertebrate embryonic prosencephalon gives rise to the hypothalamus, which plays essential roles in sensory information processing as well as control of physiological homeostasis and behaviour.
Michelle eWare, Houda eHamdi-Rozé, Valérie eDupé   +2 more
doaj   +1 more source

Exogenous spermidine affects polyamine metabolism in the mouse hypothalamus

Open Life Sciences, 2021
Spermidine is important for the hypothalamic control of pituitary secretion of hormones involved in neuroendocrine functions in mammals. In this study, the effect of exogenous spermidine on the expression of genes and proteins related to polyamine ...
Jiang Dongmei, Mo Guilin, Jiang Yilong, Kang Bo   +3 more
doaj   +1 more source

Transcriptomics analysis unveils key potential genes associated with brain development and feeding behavior in the hypothalamus of L-citrulline-fed broiler chickens

Poultry Science, 2023
: High ambient temperature is a major environmental stressor affecting poultry production, especially in the tropical and subtropical regions of the world. Nutritional interventions have been adopted to combat thermal stress in poultry, including the use
Victoria Anthony Uyanga, Semiu Folaniyi Bello, Xin Qian, Ning Chao, Haifang Li, Jingpeng Zhao, Xiaojuan Wang, Hongchao Jiao, Okanlawon M. Onagbesan, Hai Lin   +9 more
doaj   +1 more source

Transcriptome analysis of Shank3-overexpressing mice reveals unique molecular changes in the hypothalamus

Molecular Brain, 2018
Various mutations in the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene are associated with neurodevelopmental and neuropsychiatric disorders.
Chunmei Jin, Hyojin Kang, Shinhyun Kim, Yinhua Zhang, Yeunkum Lee, Yoonhee Kim, Kihoon Han   +6 more
doaj   +1 more source

Circulating free fatty acids, insulin, and glucose during chemical stimulation of hypothalamus in rats [PDF]

, 1984
The aim of this study was to investigate plasma free fatty acids (FFA), insulin, and blood glucose during chemical stimulation of the lateral and ventromedial hypothalamic areas (LHA and VMH) in rats.
Steffens, A.B., P. G. Luiten, van der Gugten, J., Steffens, A.B.,, Gugten, J. van der,, J. van der Gugten, Luiten, P.G.M., A. B. Steffens, Luiten, P.G.M.,, Damsma, G., G. Damsma, Damsma, G.,   +11 more
core   +1 more source

The Hypothalamus and Obesity [PDF]

Recent Patents on CNS Drug Discovery, 2006
Obesity has reached epidemic proportions across the developed world. Even though there have been numerous scientific advances in terms of the understanding of the regulation of energy homeostasis, few novel anti-obesity drugs have emerged. Furthermore, those that are available have limited efficacy in producing and maintaining a weight loss beyond 10%.
Joanne A, Harrold, Jason C G, Halford
openaire   +2 more sources

Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response

Frontiers in Cellular Neuroscience, 2020
Huntingtin-associated protein 1 (Hap1) was initially identified as a brain-enriched protein that binds to the Huntington’s disease protein, huntingtin. Unlike huntingtin that is ubiquitously expressed in the brain, Hap1 is enriched in the brain with the ...
Xingxing Chen, Xingxing Chen, Xingxing Chen, Ning Xin, Yongcheng Pan, Yongcheng Pan, Louyin Zhu, Peng Yin, Qiong Liu, Qiong Liu, Weili Yang, Xingshun Xu, Shihua Li, Xiao-Jiang Li   +13 more
doaj   +1 more source

Maternal glucose intolerance during pregnancy affects offspring POMC expression and results in adult metabolic alterations in a sex-dependent manner

Frontiers in Endocrinology, 2023
IntroductionGestational diabetes (GDM) is associated with negative outcomes in mothers and their offspring, including greater risks of macrosomia at birth and the development of metabolic disorders.
Marina Galleazzo Martins, Marina Galleazzo Martins, Zachary Silver, Kiara Ayoub, Lindsay Hyland, Barbara Woodside, Ana Carolina Inhasz Kiss, Ana Carolina Inhasz Kiss, Alfonso Abizaid   +8 more
doaj   +1 more source

Leptin mediates the increase in blood pressure associated with obesity [PDF]

, 2014
Obesity is associated with increased blood pressure (BP), which in turn increases the risk of cardiovascular diseases. We found that the increase in leptin levels seen in diet-induced obesity (DIO) drives an increase in BP in rodents, an effect that was ...
Cowley, Michael A., Ravussin, E., Cowley, M., Elmquist, Joel K., Myers, M., Enriori, P., Spanswick, D., O’Rahilly, S. (Stephen), Myers, Martin G., Henning, Elana, Licinio, Julio, Simonds, Stephanie E., Greenway, Frank L., Simonds, S., Farooqi, I., Brown, Russell D., Allen, A., Brown, R., Spanswick, David C., Dileone, R., Farooqi, I. Sadaf, Allen, Andrew M., Elmquist, J., Bassi, J., O’Rahilly, Stephen, Keogh, Julia M., Keogh, J., Sternson, S., Myer, Martin G., Greenway, F., Licinio, J., Enriori, Pablo J., Pryor, J., Pryor, Jack T., Dileone, Ralph, Grove, Kevin L., O’Rahilly, S., Henning, E., Ravussin, Eric, Bassi, Jaspreet, Sternson, Scott M., Grove, K.   +41 more
core   +1 more source

An Integrated Event-Driven Real-Time Tactical–Operational Optimization Framework for Smart Port Operations Planning

Logistics
The ongoing issues in global supply chain disruptions have raised many concerns of port productivity, among which port congestion is a key issue.
Danilo Abril, Carlos D. Paternina-Arboleda, Jesus Velasquez-Bermudez   +2 more
doaj   +1 more source