Blast-induced traumatic brain injury (bTBI) frequently results in sleep and circadian rhythm disturbances. We have investigated whether dysregulation of circadian rhythm after bTBI is mediated by dysregulation of clock genes in the hypothalamus and ...
Manoj Govindarajulu +4 more
doaj +1 more source
Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Nunez, Cristina +13 more
core +3 more sources
Characterization of N6-Cyclohexyladenosine-Induced Hypothermia in Syrian Hamsters
The N6-cyclohexyladenosine (CHA)-induced hypothermia in Syrian hamsters was characterized as follows: intracerebroventricular injection of CHA-induced hypothermia and the potency was increased by lowering the ambient temperature.
Mitsuteru Shintani +3 more
doaj +1 more source
The article presents analysis of the results of the original histochemical studies of tigroid substance of neurons of the lateral preoptic nucleus of hypothalamus in mature and old rats under the influence of different light modes. In all observations,
R. Bulyk +4 more
doaj +1 more source
Descending pathways from hypothalamus to dorsal motor vagus and ambiguus nuclei in the rat [PDF]
The anatomical pathways between the hypothalamus and cell groups of the lower medulla that are involved in the neural control of endocrine pancreas activity were investigated.
KUIPERS, F +9 more
core +1 more source
Role of hypothalamus function in metabolic diseases and its potential mechanisms [PDF]
The hypothalamus, a crucial neuroendocrine regulatory center, plays a significant role in the occurrence and development of metabolic diseases. Recent advances in molecular biology and imaging technology have facilitated a better understanding of the ...
Xinyu Zhang +4 more
doaj +2 more sources
Identification of sex hormone-binding globulin in the human hypothalamus [PDF]
Gonadal steroids are known to influence hypothalamic functions through both genomic and non-genomic pathways. Sex hormone-binding globulin ( SHBG) may act by a non-genomic mechanism independent of classical steroid receptors.
Caldwell, Jack D. +7 more
core +1 more source
The Visually Related Posterior Pretectal Nucleus in the Non-Percomorph Teleost Osteoglossum bicirrhosum Projects to the Hypothalamus [PDF]
This study was done to elucidate the ancestral (plesiomorphic) condition for visual pathways to the hypothalamus in teleost fishes. Three patterns of pretectal organization can be discerned morphologically and histochemically in teleosts. Their taxonomic
Wullimann, M. +8 more
core +1 more source
The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system [PDF]
INTRODUCTION: Ghrelin and cannabinoids stimulate appetite, this effect possibly being mediated by the activation of hypothalamic AMP-activated protein kinase (AMPK), a key enzyme in appetite and metabolism regulation. The cannabinoid receptor type 1 (CB1)
Judith Harvey-White +59 more
core +3 more sources
Both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are important epigenetic modifications in neurodevelopment. However, there is little research examining the genome-wide patterns of 5mC and 5hmC in brain regions of animals under natural high-
Zhixin Chai +8 more
doaj +1 more source

