Results 41 to 50 of about 204,951 (302)

Leptin mediates the increase in blood pressure associated with obesity [PDF]

, 2014
Obesity is associated with increased blood pressure (BP), which in turn increases the risk of cardiovascular diseases. We found that the increase in leptin levels seen in diet-induced obesity (DIO) drives an increase in BP in rodents, an effect that was ...
Cowley, Michael A., Ravussin, E., Cowley, M., Elmquist, Joel K., Myers, M., Enriori, P., Spanswick, D., O’Rahilly, S. (Stephen), Myers, Martin G., Henning, Elana, Licinio, Julio, Simonds, Stephanie E., Greenway, Frank L., Simonds, S., Farooqi, I., Brown, Russell D., Allen, A., Brown, R., Spanswick, David C., Dileone, R., Farooqi, I. Sadaf, Allen, Andrew M., Elmquist, J., Bassi, J., O’Rahilly, Stephen, Keogh, Julia M., Keogh, J., Sternson, S., Myer, Martin G., Greenway, F., Licinio, J., Enriori, Pablo J., Pryor, J., Pryor, Jack T., Dileone, Ralph, Grove, Kevin L., O’Rahilly, S., Henning, E., Ravussin, Eric, Bassi, Jaspreet, Sternson, Scott M., Grove, K.   +41 more
core   +2 more sources

Hypothalamic Microinflammation: New Paradigm In Obesity And Metabolic Disease

Indonesian Biomedical Journal, 2020
BACKGROUND: Hypothalamus is the master regulator of body’s systemic homeostasis including energy balance, body temperature, sleep, blood pressure, and circadian rhythms.
Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya   +2 more
doaj   +1 more source

A multi-disciplinary team model based on CBL in clinical teaching of hypothalamus-pituitary diseases [PDF]

Jichu yixue yu linchuang, 2020
Objective To explore the effect of case-based learning (CBL) combined with hypothalamus-pituitary MDT clinic in clinical teaching of hypothalamus pituitary diseases. Methods The trainees who participated in the hypothalamus-pituitary MDT discussion and
DUAN Lian, ZHENG Guang-yao, LU Lin, ZHU Hui-juan, YAO Yong, PAN Hui
doaj  

Síntomas gastrointestinales como manifestación de neuromielitis óptica: un reporte de caso

Medicina U.P.B., 2022
Se presenta el caso de una mujer en la quinta década de la vida que ingresa al servicio de urgencias con manifestaciones gastrointestinales consistentes en vómito e hipo.
Diego Fernando Abreo Leal, Tatiana Arroyave Peña, Juan Esteban Quiroz Álvarez   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Activation of the hypothalamus characterizes the response to acupuncture stimulation in heroin addicts [PDF]

, 2007
Acupuncture stimulation elicited a composite of sensations termed deqi that is related to clinical efficacy. Neurobiological studies have identified the hypothalamus as an important component in mediating the deqi.
Li, Ronghui, Lee, Tatia, Hu, Jun, W. H. Zhou, Zhou, Wenhua, Yang, Guodong, Liu, Sheng, Weng, Xuchu, Ruan, Xingzhong   +8 more
core   +1 more source

MORPHOLOGICAL AND HORMONAL STUDIES RELATED TO AGEING CHANGES OF HYPOTHALAMO-PITUITARY GLAND IN RABBITS

The Iraqi Journal of Medical Sciences, 2016
Background:The hypothalamic - pituitary axis is an auto-regulating system that realizes a tight integration among the endocrine, nervous and immune systems. Objective:To identify anatomical and microscopical age changes of hypothalamus-pituitary gland.
Idris Kh Thamer, Haider AR Ja'afar, Abdul-Karim S Mahood   +2 more
doaj   +4 more sources

Identification and characterization of a MBP isoform specific to hypothalamus in orange-spotted grouper (Epinephelus coioides) [PDF]

, 2007
Myelin basic protein (MBP), as a major component of the myelin sheath, has been revealed to play an important role informing and maintaining myelin structure in vertebrate nervous system.
Gui, J. F., Gui, JF, Chinese Acad Sci, Chinese Acad Sci, Inst Hydrobiol, Wuhan Ctr Dev Biol,State Key Lab Freshwater Ecol, Wuhan 430072, Peoples R China, Yao, B., Li, C. J., Xia, W., Zhou, L., Wang, Y., Jin, J. Y.   +7 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source