Results 41 to 50 of about 202,089 (261)

Selective infusion of CORT into the hypothalamus increases the level of CORT in the hypothalamus persistently.

, 2014
(A) Representative photo indicated the target of the infusion (the left PVN region of the hypothalamus). 3V: third ventricle. (B) The concentration of CORT in the whole hypothalamus 24 h after infusion of CORT. n = 3 for each group. (C) The concentration
Meng-Ying Liu (565119), Xiao Liu (65413), Hai-Yin Wu (565120), Zhou Han (490317), Hai-Hui Zhou (565122), Huan Li (120482), Qi-Gang Zhou (565125), Xing Jing (565121), Hoonkyo Suh (565123), Li-Juan Zhu (565118), Chen Chen (6544), Dong-Ya Zhu (565124)   +11 more
core   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

Single-cell clusters of mouse embryonic hypothalamus identified by PanoView.

, 2019
(A) Visualization of identified cell types from embryonic hypothalamus using t-SNE. (B) Relative expression of 12 selected marker genes in embryonic hypothalamus.
Ming-Wen Hu (7330190), Sheng Liu (279488), Dong Won Kim (2256052), Seth Blackshaw (1586), Donald J. Zack (7330193), Jiang Qian (771)   +5 more
core   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

Advanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu, Shanyao Liu, Haixin Liang, Jiani Yang, Yanhe Li, Jiqing Yin, Xueguang Zhang, Yan Zhang, Dandan Bai, Zihui Yan, Zhuoao Zhang, Yanping Jia, Kuisheng Liu, Yifan Sheng, Jiani Xiang, Chenxiang Xi, Baoxing Dong, Xinyi Lei, Jiayu Chen, Hong Wang, Yi Guo, Yanping Zhang, Shaorong Gao, Wenqiang Liu   +23 more
wiley   +1 more source

Exercise and ER stress in hypothalamus.

, 2013
Overnutrition increases hypothalamic activation of IKKβ/NF-κB and ER stress (they enhance each other), which leads to insulin and leptin resistance in the hypothalamus, hyperphagia, and obesity.
Miguel López (3212742), Pablo Blanco Martínez de Morentin (362295)   +1 more
core   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Mammillary bodies of hypothalamus

, 1997
Mammillary bodies of hypothalamus. Posterio hypothalamus. Coronal plane.

core  

Hypothalamus and respiratory minute volume

, 1960
Minute volume of respiration was measured in 21 cats. Hypodermic tubing and electrodes were implanted in the hypothalamus. Minute volume of respiration was measured before and after depression of the hypothalamus by coagulation with high frequency ...
Edward S. Redgate
core   +1 more source

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

Advanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia, Siyu Li, Songming Tang, Keju Gu, Shengquan Chen   +4 more
wiley   +1 more source

Activation of the hypothalamus characterizes the response to acupuncture stimulation in heroin addicts [PDF]

, 2007
Acupuncture stimulation elicited a composite of sensations termed deqi that is related to clinical efficacy. Neurobiological studies have identified the hypothalamus as an important component in mediating the deqi.
Li, Ronghui, Lee, Tatia, Hu, Jun, W. H. Zhou, Zhou, Wenhua, Yang, Guodong, Liu, Sheng, Weng, Xuchu, Ruan, Xingzhong   +8 more
core