Results 31 to 40 of about 302,233 (277)

Trypanosoma brucei brucei invasion and T-cell infiltration of the brain parenchyma in experimental sleeping sickness: timing and correlation with functional changes [PDF]

, 2016
Background: The timing of Trypanosoma brucei entry into the brain parenchyma to initiate the second, meningoencephalitic stage of human African trypanosomiasis or sleeping sickness is currently debated and even parasite invasion of the neuropil has ...
Bentivoglio, Marina, Bradley, Barbara, Etet, Paul F. Seke, Grassi-Zucconi, Gigliola, Kennedy, Peter G.E., Laperchia, Claudia, Montague, Paul, Palomba, Maria, Rodgers, Jean   +8 more
core   +4 more sources

Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response

Frontiers in Cellular Neuroscience, 2020
Huntingtin-associated protein 1 (Hap1) was initially identified as a brain-enriched protein that binds to the Huntington’s disease protein, huntingtin. Unlike huntingtin that is ubiquitously expressed in the brain, Hap1 is enriched in the brain with the ...
Xingxing Chen, Xingxing Chen, Xingxing Chen, Ning Xin, Yongcheng Pan, Yongcheng Pan, Louyin Zhu, Peng Yin, Qiong Liu, Qiong Liu, Weili Yang, Xingshun Xu, Shihua Li, Xiao-Jiang Li   +13 more
doaj   +1 more source

Hypothalamus

, 2013
A major function of the nervous system is to maintain the constancy of the internal environment. In 1878, Claude Bernard pointed out the remarkable distinction between our highly variable external environment (i.e., the environment that we live in and that is subject to major changes with regard to temperature, humidity, and food availability) and our ...
Sheina Orbell, Havah Schneider, Sabrina Esbitt, Jeffrey S. Gonzalez, Jeffrey S. Gonzalez, Erica Shreck, Abigail Batchelder, Yori Gidron, Sarah D. Pressman, Emily D. Hooker, Deborah J. Wiebe, Deborah Rinehart, Laura L. Hayman, Luigi Meneghini, Hiroe Kikuchi, Hiroe Kikuchi, Tamer F. Desouky, Lisa M. McAndrew, Pablo A. Mora, Bonnie Bruce, Tana M. Luger, Peter Allebeck, Peter Allebeck, Peter Allebeck, Olveen Carrasquillo, Alfred L. McAlister, Kristine M. Molina, Stephen Birch, Amiram Gafni, Linda C. Baumann, Alyssa Karel, Howard Sollins, Catharina Hjortsberg, Lee Sanders, Yori Gidron, Erin N. Marcus, Olveen Carrasquillo, Vincent Tran, Peter Allebeck, Maartje Wit, Tibor Hajos, Yori Gidron, Sheah Rarback, Margaret Wallhagen, Margaret Wallhagen, Siqin Ye, Jonathan Newman, William Whang, Mark Hamer, Timothy W. Smith, Scott DeBerard, Peter A. Shapiro, Yoichi Chida, Valerie Sabol, Annie T. Ginty, Julian F. Thayer, Yoshinobu Kanda, Jonathan Newman, Carrie Brintz, Timothy Whittaker, Jennifer Wessel, Laura Rodriguez-Murillo, Rany M. Salem, Yutaka Matsuyama, J. Rick Turner, Neil Schneiderman, John Ruiz, Mariana Garza, Lauren Smith, Scott DeBerard, Nicole Overstreet, Jason W. Mitchell, Olveen Carrasquillo, Osvaldo Rodriguez, Jens Gaab, Siqin Ye, Laura Rodriguez-Murillo, Rany M. Salem, Yori Gidron, Oliver T. Wolf, Andrea Croom, Hollie B. Pellosmaa, Tamer F. Desouky, Steven C. Palmer, Kimberly M. Henderson, Susan A. Everson-Rose, Cari J. Clark, Susan A. Everson-Rose, Cari J. Clark, Kimberly M. Henderson, Susan A. Everson-Rose, Cari J. Clark, Kimberly M. Henderson, Kimberly M. Henderson, Susan A. Everson-Rose, Cari J. Clark, Jonathan Z. Bakdash, Frank A. Drews, Rany M. Salem, Laura Rodriguez-Murillo, Luis I. García, Lynnee Roane, Michael James Coons, Alyssa Parker, Kelly Flannery, Douglas Carroll, Leah Rosenberg, Molly S. Clark, Katherine T. Fortenberry, Kate L. Jansen, Alyssa Parker, Jennifer Heaney, Elliott A. Beaton, J. Rick Turner   +113 more
  +8 more sources

An Integrated Event-Driven Real-Time Tactical–Operational Optimization Framework for Smart Port Operations Planning

Logistics
The ongoing issues in global supply chain disruptions have raised many concerns of port productivity, among which port congestion is a key issue.
Danilo Abril, Carlos D. Paternina-Arboleda, Jesus Velasquez-Bermudez   +2 more
doaj   +1 more source

Hypothalamic Microinflammation: New Paradigm In Obesity And Metabolic Disease

Indonesian Biomedical Journal, 2020
BACKGROUND: Hypothalamus is the master regulator of body’s systemic homeostasis including energy balance, body temperature, sleep, blood pressure, and circadian rhythms.
Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya   +2 more
doaj   +1 more source

Maternal glucose intolerance during pregnancy affects offspring POMC expression and results in adult metabolic alterations in a sex-dependent manner

Frontiers in Endocrinology, 2023
IntroductionGestational diabetes (GDM) is associated with negative outcomes in mothers and their offspring, including greater risks of macrosomia at birth and the development of metabolic disorders.
Marina Galleazzo Martins, Marina Galleazzo Martins, Zachary Silver, Kiara Ayoub, Lindsay Hyland, Barbara Woodside, Ana Carolina Inhasz Kiss, Ana Carolina Inhasz Kiss, Alfonso Abizaid   +8 more
doaj   +1 more source

Circulating free fatty acids, insulin, and glucose during chemical stimulation of hypothalamus in rats [PDF]

, 1984
The aim of this study was to investigate plasma free fatty acids (FFA), insulin, and blood glucose during chemical stimulation of the lateral and ventromedial hypothalamic areas (LHA and VMH) in rats.
Damsma, G.,, Gugten, J. van der,, Luiten, P.G.M.,, Steffens, A.B.,   +3 more
core   +1 more source

A multi-disciplinary team model based on CBL in clinical teaching of hypothalamus-pituitary diseases [PDF]

Jichu yixue yu linchuang, 2020
Objective To explore the effect of case-based learning (CBL) combined with hypothalamus-pituitary MDT clinic in clinical teaching of hypothalamus pituitary diseases. Methods The trainees who participated in the hypothalamus-pituitary MDT discussion and
DUAN Lian, ZHENG Guang-yao, LU Lin, ZHU Hui-juan, YAO Yong, PAN Hui
doaj  

Conditional knockout of leptin receptor in neural stem cells leads to obesity in mice and affects neuronal differentiation in the hypothalamus early after birth

Molecular Brain, 2020
Leptin, secreted by peripheral adipocytes, binds the leptin receptor (Lepr) in the hypothalamus, thereby contributing to the regulation of satiety and body weight. Lepr is expressed in the embryonic brain as early as embryonic day 12.5.
Zhonggan Ren, Yitong Liu, Wentong Hong, Xinjie Pan, Pifang Gong, Qiong Liu, Guomin Zhou, Song Qin   +7 more
doaj   +1 more source

Interaction of hypothalamic GABA\u3csub\u3eA\u3c/sub\u3e and excitatory amino acid receptors controlling heart rate in rats [PDF]

, 1991
We have previously shown that microinjection of drugs that impair gamma-aminobutyric acid (GABA)-mediated synaptic inhibition into the dorsomedial hypothalamus (DMH) of rats generates cardiovascular and behavioral changes that mimic the response to ...
DiMicco, Joseph A., Soltis, Robert P.
core   +2 more sources