Results 11 to 20 of about 192,010 (311)
Science, 2023 Neural substrates of wakefulness, rapid eye movement sleep (REMS), and non-REMS (NREMS) in the mammalian hypothalamus overlap both anatomically and functionally with cellular networks that support physiological and behavioral homeostasis. Here, we review
de Lecea, Luis +3 more
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Current Biology, 2014 SummaryThe hypothalamus is one of the oldest and smallest parts of the brain, constituting just 4 gm of the 1400 gm of adult human brain weight. And yet this tiny area contains highly conserved neural circuitry that controls basic life functions: these ...
Lowell, Bradford B., Saper, Clifford B.
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MicroRNAs in the Hypothalamus [PDF]
Neuroendocrinology, 2013 MicroRNAs (miRNAs) are short (∼22 nucleotides) non-coding ribonucleic acid (RNA) molecules that negatively regulate the expression of protein-coding genes. Posttranscriptional silencing of target genes by miRNA is initiated by binding to the 3′-untranslated regions of target mRNAs, resulting in specific cleavage and subsequent degradation of the mRNA ...
Meister, Björn +2 more
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Blooming in the Hypothalamus [PDF]
Journal of Neurosciences in Rural Practice, 2019 ABSTRACTCavernomas are vascular malformations which are collections of endothelium-lined sinusoids without intervening cerebral parenchyma. Hypothalamic location of cavernoma is extremely rare. We present a case of a 34-year-old male who presented with complaints of recent memory loss and vomiting.
Rai, Santosh P. V. +3 more
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Identification of sex hormone-binding globulin in the human hypothalamus [PDF]
, 2005 Gonadal steroids are known to influence hypothalamic functions through both genomic and non-genomic pathways. Sex hormone-binding globulin ( SHBG) may act by a non-genomic mechanism independent of classical steroid receptors.
Caldwell, Jack D. +7 more
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Role of hypothalamus function in metabolic diseases and its potential mechanisms [PDF]
PeerJThe hypothalamus, a crucial neuroendocrine regulatory center, plays a significant role in the occurrence and development of metabolic diseases. Recent advances in molecular biology and imaging technology have facilitated a better understanding of the ...
Xinyu Zhang +4 more
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Frontiers in Genetics, 2021 Both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are important epigenetic modifications in neurodevelopment. However, there is little research examining the genome-wide patterns of 5mC and 5hmC in brain regions of animals under natural high-
Zhixin Chai +8 more
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Descending pathways from hypothalamus to dorsal motor vagus and ambiguus nuclei in the rat [PDF]
, 1984 The anatomical pathways between the hypothalamus and cell groups of the lower medulla that are involved in the neural control of endocrine pancreas activity were investigated.
KUIPERS, F +9 more
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The Visually Related Posterior Pretectal Nucleus in the Non-Percomorph Teleost Osteoglossum bicirrhosum Projects to the Hypothalamus [PDF]
, 1991 This study was done to elucidate the ancestral (plesiomorphic) condition for visual pathways to the hypothalamus in teleost fishes. Three patterns of pretectal organization can be discerned morphologically and histochemically in teleosts. Their taxonomic
Wullimann, M. +8 more
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Hypersomnia associated with bilateral posterior hypothalamic lesion - A polysomnographic case study [PDF]
, 2003 We examined an obese 58-year-old patient with a bilateral posterior hypothalamic lesion of unknown etiology. A 24-hour polysomnography revealed a markedly increased total sleep time (17.6 h). During daytime, only 3 continuous wake phases occurred.
Uttner, I. +6 more
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