Results 11 to 20 of about 302,233 (277)
Both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are important epigenetic modifications in neurodevelopment. However, there is little research examining the genome-wide patterns of 5mC and 5hmC in brain regions of animals under natural high-
Zhixin Chai +8 more
doaj +1 more source
Disruption of type 3 adenylyl cyclase expression in the hypothalamus leads to obesity [PDF]
Evidence from human studies and transgenic mice lacking the type 3 adenylyl cyclase (AC3) indicates that AC3 plays a role in the regulation of body weight. It is unknown in which brain region AC3 exerts such an effect.
Cao, Hong +3 more
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Characterization of N6-Cyclohexyladenosine-Induced Hypothermia in Syrian Hamsters
The N6-cyclohexyladenosine (CHA)-induced hypothermia in Syrian hamsters was characterized as follows: intracerebroventricular injection of CHA-induced hypothermia and the potency was increased by lowering the ambient temperature.
Mitsuteru Shintani +3 more
doaj +1 more source
Hypersomnia associated with bilateral posterior hypothalamic lesion - A polysomnographic case study [PDF]
We examined an obese 58-year-old patient with a bilateral posterior hypothalamic lesion of unknown etiology. A 24-hour polysomnography revealed a markedly increased total sleep time (17.6 h). During daytime, only 3 continuous wake phases occurred.
Eisensehr, Ilonka +6 more
core +1 more source
Role of hypothalamus function in metabolic diseases and its potential mechanisms [PDF]
The hypothalamus, a crucial neuroendocrine regulatory center, plays a significant role in the occurrence and development of metabolic diseases. Recent advances in molecular biology and imaging technology have facilitated a better understanding of the ...
Xinyu Zhang +4 more
doaj +2 more sources
The Visually Related Posterior Pretectal Nucleus in the Non-Percomorph Teleost Osteoglossum bicirrhosum Projects to the Hypothalamus [PDF]
This study was done to elucidate the ancestral (plesiomorphic) condition for visual pathways to the hypothalamus in teleost fishes. Three patterns of pretectal organization can be discerned morphologically and histochemically in teleosts. Their taxonomic
Baudelot +51 more
core +1 more source
The article presents analysis of the results of the original histochemical studies of tigroid substance of neurons of the lateral preoptic nucleus of hypothalamus in mature and old rats under the influence of different light modes. In all observations,
R. Bulyk +4 more
doaj +1 more source
GABA\u3csub\u3eA\u3c/sub\u3e and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats [PDF]
We have previously shown that microinjection of drugs that interfere with the function of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) into the hypothalamus produces cardiorespiratory and behavioral changes resembling those seen in ...
DiMicco, Joseph A., Soltis, Robert P.
core +2 more sources
It takes two to tango: NAD+ and sirtuins in aging/longevity control [PDF]
The coupling of nicotinamide adenine dinucleotide (NAD+) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD+ and sirtuins has an ancient origin and provides a ...
Guarente, Leonard, Imai, Shin-ichiro
core +2 more sources
Abstract In a normal physiologic state, the hypothalamus plays a role in coordinating endocrine function, regulating autonomics, consolidating environmental input, and managing temperature and appetite. Pathology involving the hypothalamus may lead to conditions requiring expertise for a safe anesthetic.
Zack Powers, Chris Giordano
+7 more sources

