Results 41 to 50 of about 506,669 (258)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Revista Brasileira de Cineantropometria e Desempenho Humano, 2016 The aim of the present study was to evaluate the effects of human head hair on performance and thermoregulatory responses during 10-km outdoor running in healthy men. Twelve healthy males (29.5 ± 3.7 years, 174.9 ± 4.3 cm, 72.7 ± 3.2 kg and VO2max 44.6 ±
Angelo Ruediger Pisani Martini +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Female thermal sensitivity and behaviour across the lifespan: A unique journey
Experimental PhysiologyWomen are a group of individuals that undergo unique anatomical, physiological and hormonal changes across the lifespan. For example, consider the impact of the menstrual cycle, pregnancy and menopause, all of which are accompanied by both short‐ and ...
Davide Filingeri +2 more
doaj +1 more source
Frontiers in Sports and Active LivingObjectivesThis study aimed to investigate the influence of body composition variables, focusing on the extracellular water level and gender difference, on infrared thermography detection during and post exercise.MethodOne hundred two participants were ...
Alessandra Amato +6 more
doaj +1 more source
Heatstroke‐like symptoms in a patient with coronavirus disease pneumonia
Clinical Case Reports, 2020 While there are no clear indications for body temperature control during viral infections such as COVID‐19, if heat stress caused by COVID‐19 leads to organ failure, then proactive body temperature regulation may be an effective treatment option.
Ryo Deguchi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Frontiers in AnesthesiologyPerioperative shivering (POS) is a common complication during anesthesia recovery and has traditionally been regarded as a simple thermoregulatory response.
Chaoran Liu +8 more
doaj +1 more source
Molecular Metabolism, 2019 Objective: c-Jun, a prominent member of the activator protein 1 (AP-1) family, is involved in various physiology processes such as cell death and survival. However, a role of hepatic c-Jun in the whole-body metabolism is poorly understood.
Fei Xiao +17 more
doaj +1 more source