Results 141 to 150 of about 1,349,269 (263)

Body weight changes and longitudinal associations with cognitive decline among community-dwelling older adults. [PDF]

Alzheimers Dement (Amst), 2021
Eymundsdottir H, Ramel A, Geirsdottir OG, Skuladottir SS, Gudmundsson LS, Jonsson PV, Gudnason V, Launer L, Jonsdottir MK, Chang M.   +9 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Mapping quantitative trait loci underlying body weight changes that act at different times during high-fat diet challenge in collaborative cross mice. [PDF]

Animal Model Exp Med
Abu-Toamih Atamni HJ, Lone IM, Binenbaum I, Midlej K, Pilalis E, Mott R, Chatziioannou A, Iraqi FA.   +7 more
europepmc   +1 more source

Changes in Endogenous Oxytocin Levels and the Effects of Exogenous Oxytocin Administration on Body Weight Changes and Food Intake in Polycystic Ovary Syndrome Model Rats. [PDF]

Int J Mol Sci, 2022
Yamamoto S, Noguchi H, Takeda A, Arakaki R, Uchishiba M, Imaizumi J, Minato S, Kamada S, Kagawa T, Yoshida A, Kawakita T, Yamamoto Y, Yoshida K, Kon M, Shinohara N, Iwasa T.   +15 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

The effect of marital transition on body weight changes among Indonesian adults: A Longitudinal study. [PDF]

SSM Popul Health
Maretalinia, Jampaklay A, Sawangdee Y, Hunchangsith P, Teerawichitchainan B.   +4 more
europepmc   +1 more source

Body weight changes in the NutriNet Brasil cohort during the covid-19 pandemic. [PDF]

Rev Saude Publica, 2021
Costa CDS, Steele EM, Leite MA, Rauber F, Levy RB, Monteiro CA.   +5 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Charting a course on the effects of ocean and sea transportation stress on cattle and sheep body weight changes, behavior, and nutrient mobilization. [PDF]

Anim Front
Reichhardt CC, Blad TJ, Bustamante Y, Odani JS, Oshiro MA, Rojas-Reyes JA.   +5 more
europepmc   +1 more source