Results 121 to 130 of about 3,320,190 (287)

Influence of hypokinesis on physiological functions in fowl [PDF]

The effects of hypokinesis and postincubation stress (which are characteristic for modern techniques of poultry cage keeping) on the endocrine functions, metabolic reactions, body weight growth and proteosynthesis in the muscle of cocks was investigated.
Cierna, V., Lamosova, D., Nvota, J., Tesarova, D., Vyboh, P.   +4 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Body weight changes in female patients with prolactinoma treated with bromocriptin [PDF]

Medicinski Glasnik, 2007
The aim of this study was to determine the body weight changes in female patients with bromocriptin treated prolactinoma. Seventeen hyperprolactinemic pre-menopausal female with prolactinoma, aged 18-45 years, with body mass index (BMI) 30+/-2,1kg/m2 ...
Z. Velija-Ašimi;
doaj  

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Stress levels, eating habits, and body weight of adults in Higher Education Institutions

O Mundo da Saúde
To analyze the prevalence of perceived stress during the period of social isolation imposed by the Covid-19 pandemic, according to sociodemographic characteristics, food consumption, and other health-related behaviors, among adult workers and students ...
Gabriela Baptista, Joana Pereira de Carvalho-Ferreira, Daniela de Assumpção, Marina Padovan, Alice Helena de Souza Paulino, Caroline Dário Capitani   +5 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

A 28-Day Oral Toxicity Study in Wistar Rats for a Highly Bioavailable Curcumin Preparation, CAVACURMIN^®

Nutraceuticals
Curcumin is widely used for its antioxidant and anti-inflammatory properties, but its poor oral bioavailability has driven the development of advanced formulations such as CAVACURMIN®, a γ-cyclodextrin-based curcumin complex with enhanced absorption ...
Heiko Zipp, Marco Kellert, Natascha Lara Rivera, Sandra Schmid, Gerald Münch   +4 more
doaj   +1 more source

Body weight changes and diabetes mellitus incident: A cohort study from the Middle East. [PDF]

J Prev Med Hyg, 2023
Salesi R, Kermani-Alghoraishi M, Sadeghi A, Roohafza H, Talaei M, Sarrafzadegan N, Sadeghi M.   +6 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source